Table 3.

Ten-year serious adverse events according to the three groups of SDAI: 10-year cumulative incidence for 100 patient years

	All population (2032 PY)	REM (361 PY)	LDA (1128 PY)	MDA or HDA (532 PY)
Serious adverse events	3.34	3.60	3.01	4.14
Serious infections	1.23	1.93	0.97	1.31
Neoplasia	1.23	1.10	1.24	1.32
MACEs	0.44	0.55	0.18	0.94
Thromboembolism events	0.44	0.83	0.27	0.56
Death	0.49	0	0.53	0.75

REM patients in sustained remission, LDA patients in sustained low disease activity, MDA patients in moderate disease activity, HDA patients in sustained high disease activity, PY patient years, MACEs major cardiovascular events; all comparisons were non-significant