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. 2023 Oct 20;18:115. doi: 10.1186/s13000-023-01403-y

Table 2.

Clinicopathological features of the current cases

(A) ANHH cases.
CASE 1 CASE 2 CASE 3 CASE 4
Age (years)/Gender 24/M 54/M 49/F 34/F
Symptom HH Hypoglycemia with LOC Hypoglycemia with headache and LOC after TG HH with arrhythmia
Clinical Diagnosis ANHH Insulinoma ANHH Insulinoma
CT scan No nodule No nodule No nodule No nodule
Surgical procedure DP DP DP DP
Postoperative course No hypoglycemic symptom Occasional hypoglycemic symptom

Repeated hypoglycemic symptoms

12 years after operation, she died of ischemic heart disease

No data
Type Diffuse Diffuse Diffuse Diffuse
Site of the pancreas in a representative section Tail Tail Body Body
(B) Control cases.
CASE 1 CASE 2 CASE 3 CASE 4 CASE 5
Age (years)/Gender 74/F 46/F 65/M 69/M 65/M
Diseases pulmonary vascular injury, AAV, HLH, aspergillosis, pulmonary nocardiosis Ruptured esophageal varices, PSC, UC, LC Systemic metastasis of prostate cancer ICH, HT AP, peritonitis, ALS
Site of the pancreas in a representative section Tail Tail Head Body Body

AAV, anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis; ALS, amyotrophic lateral sclerosis; ANHH, adult nonneoplastic hyperinsulinemic hypoglycemia; AP, aspiration pneumonia; DP, distal pancreatectomy; HH hyperinsulinemic hypoglycemia; HLH, hemophagocytic lymphohistiocytosis; HT, hypertension; ICH, intracerebral hemorrhaging; LC, liver cirrhosis; LOC, loss of consciousness; PSC, primary sclerosing cholangitis; TG, total gastrectomy; UC, ulcerative colitis