Table 2.
Factors associated with non-surviving paraquat-poisoned patients
| Characteristics | Number of patients (%) | P-value | |
|---|---|---|---|
| Survivors | Non-survivors | ||
| Mean age (years ± SD) (n = 133) | 36 ± 15 | 38 ± 16 | 0.441 |
| Reason for exposure to poison (n = 127) | |||
| - Intentional | 47 (37.0) | 64 (50.4) | 0.017* |
| - Accidental | 12 (9.5) | 4 (3.1) | |
| Mean amount of paraquat ingested (ml ± SD) (n = 106) | 20.6 ± 42.1 | 206.7 ± 257.8 | 0.000* |
| Period from poison exposure to arrival at hospital (h ± SD) (n = 111) | 24.0 ± 34.4 | 13.8 ± 28.6 | 0.090 |
| Gastrointestinal tract disorder (n = 129) | |||
| - No | 11 (8.5) | 7 (5.4) | 0.127 |
| - Yes | 45 (34.9) | 66 (51.2) | |
| Renal disorder (n = 126) | |||
| - No | 28 (22.2) | 4 (3.2) | 0.000* |
| - Yes | 27 (21.4) | 67 (53.2) | |
| Pulmonary disorder (n = 127) | |||
| - No | 51 (40.2) | 17 (13.4) | 0.000* |
| - Yes | 4 (3.1) | 55 (43.3) | |
| Hepatic disorder (n = 126) | |||
| - No | 42 (33.3) | 37 (29.4) | 0.006* |
| - Yes | 13 (10.3) | 34 (27.0) | |
| Cardiovascular system disorder (n = 126) | |||
| - No | 52 (41.2) | 36 (28.6) | 0.000* |
| - Yes | 3 (2.4) | 35 (27.8) | |
| Central nervous system disorder (n = 126) | |||
| - No | 55 (43.6) | 52 (41.3) | 0.000* |
| - Yes | 0 (0.0) | 19 (15.1) | |
| Dermatological disorder (n = 126) | |||
| - No | 49 (38.9) | 64 (50.8) | 1.000 |
| - Yes | 6 (4.8) | 7 (5.5) | |
| Multiorgan failure (n = 72) | |||
| - No | 28 (38.9) | 10 (13.9) | 0.000* |
| - Yes | 0 (0.0) | 34 (47.2) | |
| Degree of severity (n = 126) | |||
| - Mild | 10 (8.0) | 0 (0.0) | 0.000* |
| - Moderate-to-severe | 45 (35.7) | 47 (37.3) | |
| - Fulminant | 0 (0.0) | 24 (19.0) | |
| Treatment for paraquat intoxication (n = 148) | |||
| - Gastric lavage | 31 (23.3) | 46 (34.6) | 0.218 |
| - Activated charcoal | 28 (21.1) | 53 (39.8) | 0.003* |
| - Hemoperfusion | 10 (7.5) | 17 (12.8) | 0.392 |
| - Cyclophosphamide | 55 (41.4) | 67 (50.4) | 1.000 |
| - Dexamethasone | 57 (42.9) | 70 (52.6) | 1.000 |
| - Vitamin C | 54 (40.6) | 61 (45.9) | 0.318 |
| - Vitamin E | 53 (39.8) | 64 (48.1) | 1.000 |
*Statistical significance