TABLE 3.
Antimicrobial activities of KSL and its analogs
| Organism | MIC (μg/ml)
|
|||||
|---|---|---|---|---|---|---|
| KSL | KSL1 | KSL2 | KSL3 | KSL4 | KSL5 | |
| Staphylococcus aureus ATCC 6538 | 3.12 | 3.12 | 3.12 | 12.5 | 12.5 | >100 |
| MRSA | 12.5 | 12.5 | 6.25 | 50 | 25 | >100 |
| Staphylococcus epidermidis ATCC 12228 | 0.78 | 0.78 | 0.78 | NAa | NA | NA |
| Micrococcus luteus ATCC 9341 | 0.78 | 0.78 | 0.78 | 3.12 | 3.12 | >100 |
| Mycobacterium smegmatis ATCC 607 | 6.25 | 3.12 | 3.12 | NA | NA | NA |
| Escherichia coli ATCC 2592 | 3.12 | 3.12 | 3.12 | 3.12 | 3.12 | 100 |
| Pseudomonas aeruginosa ATCC 9027 | 1.56 | 3.12 | 3.12 | 1.56 | 1.56 | 100 |
| Proteus vulgaris ATCC 6380 | >100 | >100 | >100 | >100 | >100 | >100 |
| Shigella flexneri ATCC 203 | 3.12 | 3.12 | 3.12 | NA | NA | NA |
| Candida albicans ATCC 36232 | 0.78 | 0.78 | 0.78 | 3.12 | 3.12 | >100 |
a
NA, not assayed.