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. 2023 Jun 20;20(9):3884–3897. doi: 10.1111/iwj.14264

TABLE 3.

The main outcomes of the meta‐analysis.

Significant factors No. of studies I 2 (%) Q test (P) OR (95% CI) P value
General factors Sex 13 15 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 26 , 27 , 28 , 29 12 0.32 1.28 (1.06, 1.55) .01 a
Age > 60 2 20 , 28 0 0.53 2.75 (1.65, 4.57) .0001 a
Smoking 5 15 , 16 , 18 , 23 , 27 47 0.11 1.99 (1.46, 2.73) <.0001 a
Diseases factors Hypertension 6 15 , 19 , 23 , 24 , 27 , 29 0 0.71 1.24 (0.94, 1.64) .12 a
Diabetes 9 15 , 19 , 20 , 22 , 23 , 24 , 27 , 28 , 29 12 0.33 2.03 (1.59, 2.61) <.00001 a
Anaemia 3 15 , 22 , 29 58 0.09 4.72 (1.66, 13.40) .004 b
Preoperative obstruction 2 22 , 28 0 0.99 3.07 (1.80, 5.23) <.0001 a
TNM ≥ III 5 15 , 18 , 19 , 20 , 23 24 0.26 2.05 (1.56, 2.70) <.00001 a
Hypoproteinemia 5 15 , 18 , 19 , 22 , 27 0 0.52 3.05 (2.08, 4.49) <.00001 a
Surgical operation factors ASA ≥ 3 5 21 , 24 , 27 , 28 , 29 0 0.78 1.22 (0.87, 1.72) .25 a
Operation time ≥3 h 2 24 , 25 0 0.39 8.33 (3.81, 18.20) <.00001 a
Surgery ways 6 15 , 21 , 23 , 24 , 27 , 29 0 0.74 2.18 (1.61, 2.94) <.00001 a
Blood transfusion 3 19 , 20 , 24 38 0.20 1.44 (1.01, 2.06) .04 a

Note: I 2 statistic was defined as the proportion of heterogeneity not due to chance or random error. The significance of statistics is shown in bold.

Abbreviations: ASA, American Society of Anesthesiologists; CI, confidence interval; OR, odds ratio; TNM, distant staging of local lymph node metastasis of primary tumour.

a

Fixed‐effects model was performed.

b

Random‐effects model was performed.