TABLE 3.
Significant factors | No. of studies | I 2 (%) | Q test (P) | OR (95% CI) | P value | |
---|---|---|---|---|---|---|
General factors | Sex | 13 15 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 26 , 27 , 28 , 29 | 12 | 0.32 | 1.28 (1.06, 1.55) | .01 a |
Age > 60 | 2 20 , 28 | 0 | 0.53 | 2.75 (1.65, 4.57) | .0001 a | |
Smoking | 5 15 , 16 , 18 , 23 , 27 | 47 | 0.11 | 1.99 (1.46, 2.73) | <.0001 a | |
Diseases factors | Hypertension | 6 15 , 19 , 23 , 24 , 27 , 29 | 0 | 0.71 | 1.24 (0.94, 1.64) | .12 a |
Diabetes | 9 15 , 19 , 20 , 22 , 23 , 24 , 27 , 28 , 29 | 12 | 0.33 | 2.03 (1.59, 2.61) | <.00001 a | |
Anaemia | 3 15 , 22 , 29 | 58 | 0.09 | 4.72 (1.66, 13.40) | .004 b | |
Preoperative obstruction | 2 22 , 28 | 0 | 0.99 | 3.07 (1.80, 5.23) | <.0001 a | |
TNM ≥ III | 5 15 , 18 , 19 , 20 , 23 | 24 | 0.26 | 2.05 (1.56, 2.70) | <.00001 a | |
Hypoproteinemia | 5 15 , 18 , 19 , 22 , 27 | 0 | 0.52 | 3.05 (2.08, 4.49) | <.00001 a | |
Surgical operation factors | ASA ≥ 3 | 5 21 , 24 , 27 , 28 , 29 | 0 | 0.78 | 1.22 (0.87, 1.72) | .25 a |
Operation time ≥3 h | 2 24 , 25 | 0 | 0.39 | 8.33 (3.81, 18.20) | <.00001 a | |
Surgery ways | 6 15 , 21 , 23 , 24 , 27 , 29 | 0 | 0.74 | 2.18 (1.61, 2.94) | <.00001 a | |
Blood transfusion | 3 19 , 20 , 24 | 38 | 0.20 | 1.44 (1.01, 2.06) | .04 a |
Note: I 2 statistic was defined as the proportion of heterogeneity not due to chance or random error. The significance of statistics is shown in bold.
Abbreviations: ASA, American Society of Anesthesiologists; CI, confidence interval; OR, odds ratio; TNM, distant staging of local lymph node metastasis of primary tumour.
Fixed‐effects model was performed.
Random‐effects model was performed.