Table 3.

TAPS device usage and effectiveness by age group and gender in the TX arm.

NUMBER OF SUBJECTS	ALL PATIENTS	AGE (YEARS)			GENDER
		<65	≥65	p VALUE	FEMALE	MALE	p VALUE
	N = 1 33	N = 38	N = 95		N = 49	N = 84
Usage patterns, Mean (SD)
Number of sessions per week	4.34 (4.12)	3.03 (2.94)	4.87 (4.41)	0.0194	4.61 (5.12)	4.19 (3.43)	0.5740
Number of days per week with at least one session	3.00 (2.17)	2.28 (1.84)	3.29 (2.23)	0.0142	2.95 (2.26)	3.03 (2.14)	0.8416
Number of sessions per day on days when therapy used	1.32 (0.49)	1.25 (0.41)	1.35 (0.52)	0.3198	1.38 (0.68)	1.29 (0.35)	0.3446
Tremor power improvement ratio1, Mean (95% CI)
Improvement ratio, all sessions	3.51 (2.46–4.56)	4.43 (2.48–6.36)	3.16 (2.20–4.10)	0.2841	2.98 (1.77–4.20)	3.81 (2.30–5.32)	0.4541
Improvement2 in BF-ADL score, Mean (SD)
Improvement in BF-ADL score	1.59 (3.07)	1.81 (1.91)	1.48 (3.50)	0.0147	1.57 (2.27	1.59 (3.35)	0.1355
BF-ADL individual task improvements2 in patients with ≥ 3 at baseline for each task, Mean (SE)
Pour milk from a bottle	0.92 (0.15) (N = 24, p < 0.0001)
Insert an electric plug	0.80 (0.21) (N = 20, p = 0.0013)
Hold a cup of tea	0.73 (0.11) (N = 40, p < 0.0001)
Dial a telephone	0.70 (0.18) (N = 20, p = 0.0009)
Use a spoon to drink soup	0.61 (0.11) (N = 46, p < 0.0001)
Unlock front door	0.50 (0.20) (N = 16, p = 0.0271)
Pick up change	0.37 (0.19) (N = 19, p = 0.0691)
Write a letter	0.31 (0.08) (N = 62, p = 0.0006)

¹ Device-measured outcome, improvement ratio was defined pre-stimulation tremor power divided post-stimulation tremor power.

² BF-ADL improvement, BF-ADL score changes defined as BF-ADL score at the end of one month minus BF-ADL score at baseline multiplied by –1. A positive value indicates improved ADL from baseline over one month.