Table 2. The Nine Genes Best Predictors Extracted From 23 Signature Genes Using the Cox-PH Model With Recursive Feature Elimination.
coef | std err | z | P > |z| | (0.025 | 0.975) | |
---|---|---|---|---|---|---|
23 genes | ||||||
const | -0.568 | 0.684 | -0.83 | 0.406 | -1.909 | 0.773 |
AGL | 0.2822 | 0.109 | 2.591 | 0.01 | 0.069 | 0.496 |
BIRC5 | 0.1692 | 0.227 | 0.747 | 0.455 | -0.275 | 0.613 |
C1orf64 | -0.216 | 0.061 | -3.565 | 0 | -0.335 | -0.097 |
CDCA3 | 0.1451 | 0.282 | 0.514 | 0.607 | -0.408 | 0.698 |
CENPF | 0.1927 | 0.243 | 0.795 | 0.427 | -0.283 | 0.668 |
CEP55 | -0.7396 | 0.378 | -1.957 | 0.05 | -1.48 | 0.001 |
CIDEC | 0.021 | 0.077 | 0.272 | 0.785 | -0.13 | 0.172 |
CKAP2L | 0.8004 | 0.44 | 1.82 | 0.069 | -0.062 | 1.663 |
CRTAP | -0.3557 | 0.197 | -1.808 | 0.071 | -0.741 | 0.03 |
CYP4F22 | -0.1655 | 0.09 | -1.845 | 0.065 | -0.341 | 0.01 |
E2F2 | -0.3632 | 0.253 | -1.434 | 0.152 | -0.86 | 0.133 |
FHL2 | -0.0056 | 0.098 | -0.057 | 0.955 | -0.197 | 0.186 |
FOS | 0.0434 | 0.077 | 0.566 | 0.571 | -0.107 | 0.194 |
GSTM2 | -0.0754 | 0.08 | -0.937 | 0.349 | -0.233 | 0.082 |
HNMT | -0.5129 | 0.213 | -2.405 | 0.016 | -0.931 | -0.095 |
KIF20A | 1.2829 | 0.324 | 3.956 | 0 | 0.647 | 1.919 |
LAD1 | 0.2009 | 0.083 | 2.423 | 0.015 | 0.038 | 0.363 |
PIP | 0.0504 | 0.044 | 1.155 | 0.248 | -0.035 | 0.136 |
PRC1 | -0.5401 | 0.27 | -2 | 0.045 | -1.069 | -0.011 |
S100P | 0.1684 | 0.047 | 3.571 | 0 | 0.076 | 0.261 |
SEPP1 | 0.2943 | 0.13 | 2.267 | 0.023 | 0.04 | 0.549 |
STAT1 | -0.0774 | 0.111 | -0.695 | 0.487 | -0.296 | 0.141 |
TUBA3D | -0.2673 | 0.074 | -3.619 | 0 | -0.412 | -0.123 |
13 genes | ||||||
const | -0.93 | 0.458 | -2.029 | 0.042 | -1.828 | -0.032 |
AGL | 0.2695 | 0.105 | 2.557 | 0.011 | 0.063 | 0.476 |
C1orf64 | -0.2189 | 0.058 | -3.774 | 0 | -0.333 | -0.105 |
CEP55 | -0.7108 | 0.353 | -2.012 | 0.044 | -1.403 | -0.019 |
CKAP2L | 0.7766 | 0.4 | 1.943 | 0.052 | -0.007 | 1.56 |
CRTAP | -0.345 | 0.184 | -1.876 | 0.061 | -0.705 | 0.015 |
CYP4F22 | -0.1731 | 0.088 | -1.96 | 0.05 | -0.346 | -3.02E-05 |
HNMT | -0.3755 | 0.198 | -1.893 | 0.058 | -0.764 | 0.013 |
KIF20A | 1.2816 | 0.307 | 4.168 | 0 | 0.679 | 1.884 |
LAD1 | 0.2107 | 0.081 | 2.611 | 0.009 | 0.053 | 0.369 |
PRC1 | -0.513 | 0.261 | -1.966 | 0.049 | -1.024 | -0.002 |
S100P | 0.1733 | 0.046 | 3.74 | 0 | 0.082 | 0.264 |
SEPP1 | 0.2812 | 0.123 | 2.277 | 0.023 | 0.039 | 0.523 |
TUBA3D | -0.2489 | 0.07 | -3.532 | 0 | -0.387 | -0.111 |
12 genes | ||||||
const | -0.9519 | 0.458 | -2.079 | 0.038 | -1.85 | -0.054 |
AGL | 0.3102 | 0.103 | 3.013 | 0.003 | 0.108 | 0.512 |
C1orf64 | -0.2124 | 0.058 | -3.668 | 0 | -0.326 | -0.099 |
CEP55 | -0.631 | 0.35 | -1.803 | 0.071 | -1.317 | 0.055 |
CKAP2L | 0.9341 | 0.392 | 2.383 | 0.017 | 0.166 | 1.702 |
CYP4F22 | -0.17 | 0.088 | -1.926 | 0.054 | -0.343 | 0.003 |
HNMT | -0.5147 | 0.184 | -2.793 | 0.005 | -0.876 | -0.153 |
KIF20A | 1.1914 | 0.303 | 3.931 | 0 | 0.597 | 1.785 |
LAD1 | 0.2105 | 0.081 | 2.603 | 0.009 | 0.052 | 0.369 |
PRC1 | -0.5702 | 0.259 | -2.202 | 0.028 | -1.078 | -0.063 |
S100P | 0.1651 | 0.046 | 3.582 | 0 | 0.075 | 0.255 |
SEPP1 | 0.183 | 0.112 | 1.636 | 0.102 | -0.036 | 0.402 |
TUBA3D | -0.2344 | 0.07 | -3.353 | 0.001 | -0.371 | -0.097 |
11 genes | ||||||
const | -0.8428 | 0.452 | -1.866 | 0.062 | -1.728 | 0.042 |
AGL | 0.3101 | 0.103 | 3.014 | 0.003 | 0.108 | 0.512 |
C1orf64 | -0.2005 | 0.057 | -3.495 | 0 | -0.313 | -0.088 |
CEP55 | -0.5666 | 0.347 | -1.632 | 0.103 | -1.247 | 0.114 |
CKAP2L | 0.8471 | 0.388 | 2.182 | 0.029 | 0.086 | 1.608 |
CYP4F22 | -0.1772 | 0.088 | -2.014 | 0.044 | -0.35 | -0.005 |
HNMT | -0.3585 | 0.157 | -2.289 | 0.022 | -0.665 | -0.051 |
KIF20A | 1.1552 | 0.302 | 3.822 | 0 | 0.563 | 1.748 |
LAD1 | 0.2013 | 0.08 | 2.501 | 0.012 | 0.044 | 0.359 |
PRC1 | -0.5527 | 0.259 | -2.134 | 0.033 | -1.06 | -0.045 |
S100P | 0.1609 | 0.046 | 3.504 | 0 | 0.071 | 0.251 |
TUBA3D | -0.2376 | 0.07 | -3.398 | 0.001 | -0.375 | -0.101 |
10 genes | ||||||
const | -0.7569 | 0.447 | -1.692 | 0.091 | -1.633 | 0.12 |
AGL | 0.2979 | 0.102 | 2.907 | 0.004 | 0.097 | 0.499 |
C1orf64 | -0.1867 | 0.057 | -3.294 | 0.001 | -0.298 | -0.076 |
CKAP2L | 0.5869 | 0.352 | 1.67 | 0.095 | -0.102 | 1.276 |
CYP4F22 | -0.1749 | 0.088 | -1.99 | 0.047 | -0.347 | -0.003 |
HNMT | -0.4006 | 0.154 | -2.602 | 0.009 | -0.702 | -0.099 |
KIF20A | 1.036 | 0.292 | 3.545 | 0 | 0.463 | 1.609 |
LAD1 | 0.1867 | 0.08 | 2.341 | 0.019 | 0.03 | 0.343 |
PRC1 | -0.6683 | 0.249 | -2.688 | 0.007 | -1.156 | -0.181 |
S100P | 0.1609 | 0.046 | 3.509 | 0 | 0.071 | 0.251 |
TUBA3D | -0.2381 | 0.07 | -3.416 | 0.001 | -0.375 | -0.101 |
9 genes | ||||||
const | -1.0651 | 0.407 | -2.617 | 0.009 | -1.863 | -0.267 |
AGL | 0.3107 | 0.102 | 3.04 | 0.002 | 0.11 | 0.511 |
C1orf64 | -0.1932 | 0.057 | -3.416 | 0.001 | -0.304 | -0.082 |
CYP4F22 | -0.176 | 0.088 | -2.009 | 0.045 | -0.348 | -0.004 |
HNMT | -0.4024 | 0.154 | -2.611 | 0.009 | -0.705 | -0.1 |
KIF20A | 1.2687 | 0.258 | 4.915 | 0 | 0.763 | 1.775 |
LAD1 | 0.1841 | 0.08 | 2.309 | 0.021 | 0.028 | 0.34 |
PRC1 | -0.4968 | 0.226 | -2.2 | 0.028 | -0.939 | -0.054 |
S100P | 0.1645 | 0.046 | 3.596 | 0 | 0.075 | 0.254 |
TUBA3D | -0.2352 | 0.07 | -3.38 | 0.001 | -0.372 | -0.099 |
Cox-PH: Cox proportional-hazards.