Table 3.

Bivariate Genetic Correlations Between the Primary Endophenotypes and the Penn CNB Measures as Assessed in the Pedigrees^a

	PPI	Antisaccade Task	CPT	CVLT	LNS	ABF	FMEM	SMEM	SPA	S-M
Antisaccade task	−0.10 ± 0.20
CPT	0.07 ± 0.21	0.42 ± 0.13b
CVLT	0.04 ± 0.26	0.06 ± 0.19	0.34 ± 0.18
LNS	0.09 ± 0.20	0.45 ± 0.14b	0.35 ± 0.15b	0.38 ± 0.17c
ABF	0.19 ± 0.26	0.34 ± 0.17	0.40 ± 1.80b	0.34 ± 0.21	0.42 ± 1.80b
FMEM	0.20 ± 0.24	0.29 ± 0.16	0.32 ± 0.16	0.38 ± 0.20b	0.26 ± 0.17	0.22 ± 0.19
SMEM	0.21 ± 0.34	0.31 ± 0.17	0.43 ± 0.21b	0.68 ± 0.23b	0.38 ± 0.21	0.87 ± 0.27c	0.61 ± 0.22b
SPA	0.41 ± 0.18b	0.46 ± 0.13c	0.57 ± 0.12c	0.49 ± 0.16b	0.45 ± 0.13c	0.76 ± 0.16c	0.46 ± 0.16b	0.49 ± 0.20b
S-M	−0.10 ± 0.21	0.16 ± 0.15	0.19 ± 0.15	−0.23 ± 0.19	0.08 ± 0.15	0.15 ± 0.18	0.10 ± 0.17	0.20 ± 0.21	0.13 ± 0.15
EMO	0.12 ± 0.23	0.32 ± 0.15	0.32 ± 0.16	0.30 ± 0.19	0.34 ± 0.16b	0.34 ± 0.19	0.58 ± 0.14b	0.56 ± 0.24b	0.47 ± 0.15b	0.21 ± 0.17

Abbreviations: ABF, Abstraction and Mental Flexibility; CPT, Continuous Performance Test; CVLT, California Verbal Learning Test; EMO, Emotion Recognition; FMEM, Face Memory; LNS, Letter-Number Sequencing test; Penn CNB, University of Pennsylvania Computerized Neurocognitive Battery; PPI, prepulse inhibition of the startle response; S-M, Sensorimotor Dexterity; SMEM, Spatial Memory; SPA, Spatial Processing.

^aCorrelation estimates and their standard errors (mean ± SE) are indicated for each pair of endophenotypes.

^bCorrelations significant at P < .05.

^cCorrelations significant at P < .001 that remain significant after correction for multiple testing.