Table 4.
Bivariate Environmental Correlations Between the Primary Endophenotypes and the Penn CNB Measures as Assessed in the Pedigreesa
| PPI | Antisaccade Task | CPT | CVLT | LNS | ABF | FMEM | SMEM | SPA | S-M | |
|---|---|---|---|---|---|---|---|---|---|---|
| Antisaccade task | 0.12 ± 0.12 | |||||||||
| CPT | 0.26 ± 0.10b | 0.34 ± 0.08c | ||||||||
| CVLT | −0.03 ± 0.10 | 0.23 ± 0.09b | 0.14 ± 0.08 | |||||||
| LNS | 0.16 ± 0.10 | 0.17 ± 0.17 | 0.19 ± 0.08b | 0.28 ± 0.08b | ||||||
| ABF | −0.03 ± 0.12 | 0.21 ± 0.09b | 0.17 ± 0.08b | 0.22 ± 0.08b | 0.14 ± 0.08 | |||||
| FMEM | 0.03 ± 0.10 | 0.34 ± 0.08c | 0.28 ± 0.08c | 0.30 ± 0.08c | 0.17 ± 0.08b | 0.30 ± 0.08c | ||||
| SMEM | −0.11 ± 0.11 | 0.31 ± 0.09c | 0.08 ± 0.09 | 0.17 ± 0.08b | 0.04 ± 0.09 | 0.04 ± 0.08 | 0.24 ± 0.08b | |||
| SPA | −0.12 ± 0.38 | 0.26 ± 0.11b | 0.01 ± 0.11 | 0.22 ± 0.10b | 0.18 ± 0.10 | 0.22 ± 0.09b | 0.17 ± 0.10 | 0.15 ± 0.10 | ||
| S-M | −0.13 ± 0.28 | 0.36 ± 0.09c | 0.31 ± 0.09c | 0.33 ± 0.08c | 0.21 ± 0.09b | 0.26 ± 0.09b | 0.34 ± 0.08c | 0.20 ± 0.09b | 0.30 ± 0.11b | |
| EMO | 0.00 ± 0.01 | 0.27 ± 0.09b | 0.17 ± 0.08 | 0.23 ± 0.08b | 0.15 ± 0.09 | 0.23 ± 0.08b | 0.35 ± 0.07c | 0.06 ± 0.08 | 0.17 ± 0.10 | 0.29 ± 0.08c |
Abbreviations: ABF, Abstraction and Mental Flexibility; CPT, Continuous Performance Test; CVLT, California Verbal Learning Test; EMO, Emotion Recognition; FMEM, Face Memory; LNS, Letter-Number Sequencing test; Penn CNB, University of Pennsylvania Computerized Neurocognitive Battery; PPI, prepulse inhibition of the startle response; S-M, Sensorimotor Dexterity; SMEM, Spatial Memory; SPA, Spatial Processing.
Correlation estimates and their standard errors (mean ± SE) are indicated for each pair of endophenotypes.
Correlations significant at P < .05.
Correlations significant at P < .001 that remain significant after correction for multiple testing.