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. 2023 Oct 6;11:1236527. doi: 10.3389/fpubh.2023.1236527

Table 3.

Association between quantitative variables and quality of life outcomes, according to the different domains of the SF-36 test 1 year after hospital admission.

Quantitative variables Correlation * between quantitative variables and quality of life outcomes, according to SF-36 domain
Physical functioning Physical role Bodily pain General health Vitality Social functioning Emotional role Mental health
rs p rs p rs p rs p rs p rs p rs p rs p
Medical history
Age* (n = 486) −0.302 <0.001 −0.036 0.440 −0.054 0.230 −0.132 0.004 −0.032 0.480 0.025 0.590 0.086 0.059 0.052 0.250
Age-adjusted Charlson Comorbidity Index (n = 486) −0.294 <0.001 −0.059 0.200 −0.077 0.092 −0.166 <0.001 −0.043 0.350 0.006 0.900 0.067 0.140 0.038 0.410
Clinical outcomes
Hospital stay (days) (n = 486) −0.188 <0.001 −0.650 0.150 −0.091 0.045 −0.074 0.100 −0.016 0.720 −0.084 0.064 −0.050 0.27 0.038 0.410
ICU admission (days) (n = 100) −0.043 0.670 0.067 0.510 −0.017 0.870 0.016 0.870 0.011 0.920 −0.047 0.640 0.043 0.670 0.029 0.780
PaO2/FiO2 at admission (n = 385) 0.124 0.015 0.005 0.920 0.047 0.360 0.069 0.180 −0.035 0.490 0.038 0.460 0.040 0.430 −0.040 0.430
FiO2 at admission (%) (n = 486) −0.098 0.031 −0.021 0.640 −0.084 0.064 −0.024 0.590 0.058 0.200 −0.019 0.670 −0.034 0.460 −0.022 0.620
Min PaO2/FiO2 (n = 381) 0.017 0.750 −0.069 0.180 −0.020 0.700 −0.033 0.520 −0.132 0.010 −0.008 0.880 0.023 0.660 −0.116 0.023
Max FiO2 (%) (n = 486) −0.145 0.001 −0.006 0.900 −0.029 0.520 −0.054 0.230 0.043 0.350 −0.018 0.690 −0.048 0.290 0.035 0.440
Analytical parameters
Lymphopenia at admission (/μL) (n = 484) −0.021 0.640 −0.084 0.064 −0.077 0.089 −0.060 0.190 −0.096 0.034 −0.031 0.500 −0.070 0.880 −0.062 0.180
CRP at admission (mg/L) (n = 486) 0.017 0.720 0.089 0.049 0.075 0.100 0.086 0.058 0.150 0.001 0.033 0.470 0.057 0.210 0.114 0.010
Ferritin at admission (μg/L) (n = 443) 0.233 <0.001 0.127 0.007 0.185 <0.001 0.170 <0.001 0.222 <0.001 0.164 0.001 0.135 0.005 0.211 <0.001
IL-6 at admission (ng/L) (n = 285) 0.043 0.470 0.114 0.055 0.088 0.140 0.054 0.360 0.138 0.020 −0.017 0.780 0.066 0.270 0.106 0.073
D-dimer at admission (ng/mL) (n = 431) −0.068 0.160 −0.031 0.520 −0.034 0.480 0.003 0.950 0.030 0.540 −0.014 0.770 0.009 0.850 0.008 0.880
Min lymphocytes during admission (/μL) (n = 484) 0.045 0.320 −0.036 0.430 −0.039 0.390 −0.051 0.270 −0.069 0.130 −0.006 0.890 0.003 0.940 −0.094 0.039
Max RCP during admission (mg/L) (n = 485) −0.001 0.980 0.072 0.110 0.088 0.054 0.070 0.120 0.135 0.003 0.023 0.610 0.045 0.330 0.112 0.014
Max ferritin during admission (mcg/L) (n = 447) 0.169 <0.001 0.100 0.028 0.167 <0.001 0.153 0.001 0.177 <0.001 0.171 <0.001 0.103 0.025 0.188 <0.001
Max IL-6 during admission (ng/L) (n = 357) −0.035 0.510 0.001 0.980 0.041 0.440 −0.028 0.600 0.088 0.098 −0.063 0.240 0.004 0.950 0.031 0.570
Max d-dimer during admission (ng/mL) (n = 480) −0.124 0.006 −0.058 0.200 −0.034 0.460 <0.001 1.000 0.026 0.580 −0.046 0.320 −0.032 0.490 0.028 0.540
Total days of corticosteroid treatment (n = 486) −0.049 0.280 −0.043 0.350 0.060 0.190 −0.031 0.490 0.001 0.980 −0.014 0.750 −0.028 0.530 0.009 0.840

CRP, C reactive protein; IQR, Interquartile range. *Correlation presented as Spearman’s rho (rs), except in the case of age, where it is Pearson’s correlation coefficient.

Values in bold have reached statistical significance.