Table 3.
Association between quantitative variables and quality of life outcomes, according to the different domains of the SF-36 test 1 year after hospital admission.
Quantitative variables | Correlation * between quantitative variables and quality of life outcomes, according to SF-36 domain | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Physical functioning | Physical role | Bodily pain | General health | Vitality | Social functioning | Emotional role | Mental health | |||||||||
rs | p | rs | p | rs | p | rs | p | rs | p | rs | p | rs | p | rs | p | |
Medical history | ||||||||||||||||
Age* (n = 486) | −0.302 | <0.001 | −0.036 | 0.440 | −0.054 | 0.230 | −0.132 | 0.004 | −0.032 | 0.480 | 0.025 | 0.590 | 0.086 | 0.059 | 0.052 | 0.250 |
Age-adjusted Charlson Comorbidity Index (n = 486) | −0.294 | <0.001 | −0.059 | 0.200 | −0.077 | 0.092 | −0.166 | <0.001 | −0.043 | 0.350 | 0.006 | 0.900 | 0.067 | 0.140 | 0.038 | 0.410 |
Clinical outcomes | ||||||||||||||||
Hospital stay (days) (n = 486) | −0.188 | <0.001 | −0.650 | 0.150 | −0.091 | 0.045 | −0.074 | 0.100 | −0.016 | 0.720 | −0.084 | 0.064 | −0.050 | 0.27 | 0.038 | 0.410 |
ICU admission (days) (n = 100) | −0.043 | 0.670 | 0.067 | 0.510 | −0.017 | 0.870 | 0.016 | 0.870 | 0.011 | 0.920 | −0.047 | 0.640 | 0.043 | 0.670 | 0.029 | 0.780 |
PaO2/FiO2 at admission (n = 385) | 0.124 | 0.015 | 0.005 | 0.920 | 0.047 | 0.360 | 0.069 | 0.180 | −0.035 | 0.490 | 0.038 | 0.460 | 0.040 | 0.430 | −0.040 | 0.430 |
FiO2 at admission (%) (n = 486) | −0.098 | 0.031 | −0.021 | 0.640 | −0.084 | 0.064 | −0.024 | 0.590 | 0.058 | 0.200 | −0.019 | 0.670 | −0.034 | 0.460 | −0.022 | 0.620 |
Min PaO2/FiO2 (n = 381) | 0.017 | 0.750 | −0.069 | 0.180 | −0.020 | 0.700 | −0.033 | 0.520 | −0.132 | 0.010 | −0.008 | 0.880 | 0.023 | 0.660 | −0.116 | 0.023 |
Max FiO2 (%) (n = 486) | −0.145 | 0.001 | −0.006 | 0.900 | −0.029 | 0.520 | −0.054 | 0.230 | 0.043 | 0.350 | −0.018 | 0.690 | −0.048 | 0.290 | 0.035 | 0.440 |
Analytical parameters | ||||||||||||||||
Lymphopenia at admission (/μL) (n = 484) | −0.021 | 0.640 | −0.084 | 0.064 | −0.077 | 0.089 | −0.060 | 0.190 | −0.096 | 0.034 | −0.031 | 0.500 | −0.070 | 0.880 | −0.062 | 0.180 |
CRP at admission (mg/L) (n = 486) | 0.017 | 0.720 | 0.089 | 0.049 | 0.075 | 0.100 | 0.086 | 0.058 | 0.150 | 0.001 | 0.033 | 0.470 | 0.057 | 0.210 | 0.114 | 0.010 |
Ferritin at admission (μg/L) (n = 443) | 0.233 | <0.001 | 0.127 | 0.007 | 0.185 | <0.001 | 0.170 | <0.001 | 0.222 | <0.001 | 0.164 | 0.001 | 0.135 | 0.005 | 0.211 | <0.001 |
IL-6 at admission (ng/L) (n = 285) | 0.043 | 0.470 | 0.114 | 0.055 | 0.088 | 0.140 | 0.054 | 0.360 | 0.138 | 0.020 | −0.017 | 0.780 | 0.066 | 0.270 | 0.106 | 0.073 |
D-dimer at admission (ng/mL) (n = 431) | −0.068 | 0.160 | −0.031 | 0.520 | −0.034 | 0.480 | 0.003 | 0.950 | 0.030 | 0.540 | −0.014 | 0.770 | 0.009 | 0.850 | 0.008 | 0.880 |
Min lymphocytes during admission (/μL) (n = 484) | 0.045 | 0.320 | −0.036 | 0.430 | −0.039 | 0.390 | −0.051 | 0.270 | −0.069 | 0.130 | −0.006 | 0.890 | 0.003 | 0.940 | −0.094 | 0.039 |
Max RCP during admission (mg/L) (n = 485) | −0.001 | 0.980 | 0.072 | 0.110 | 0.088 | 0.054 | 0.070 | 0.120 | 0.135 | 0.003 | 0.023 | 0.610 | 0.045 | 0.330 | 0.112 | 0.014 |
Max ferritin during admission (mcg/L) (n = 447) | 0.169 | <0.001 | 0.100 | 0.028 | 0.167 | <0.001 | 0.153 | 0.001 | 0.177 | <0.001 | 0.171 | <0.001 | 0.103 | 0.025 | 0.188 | <0.001 |
Max IL-6 during admission (ng/L) (n = 357) | −0.035 | 0.510 | 0.001 | 0.980 | 0.041 | 0.440 | −0.028 | 0.600 | 0.088 | 0.098 | −0.063 | 0.240 | 0.004 | 0.950 | 0.031 | 0.570 |
Max d-dimer during admission (ng/mL) (n = 480) | −0.124 | 0.006 | −0.058 | 0.200 | −0.034 | 0.460 | <0.001 | 1.000 | 0.026 | 0.580 | −0.046 | 0.320 | −0.032 | 0.490 | 0.028 | 0.540 |
Total days of corticosteroid treatment (n = 486) | −0.049 | 0.280 | −0.043 | 0.350 | 0.060 | 0.190 | −0.031 | 0.490 | 0.001 | 0.980 | −0.014 | 0.750 | −0.028 | 0.530 | 0.009 | 0.840 |
CRP, C reactive protein; IQR, Interquartile range. *Correlation presented as Spearman’s rho (rs), except in the case of age, where it is Pearson’s correlation coefficient.
Values in bold have reached statistical significance.