Table 4.
Results of the multivariable linear regression analysis of the association between explanatory variables and quality of life domains on the SF-36.
| Physical functioning | Physical role | Bodily pain | General health | Vitality | Social functioning | Emotional role | Mental health | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Variables | β (95% CI) | p | β (95% CI) | p | β (95% CI) | p | β (95% CI) | p | β (95% CI) | p | β (95% CI) | p | β (95% CI) | p | β (95% CI) | p |
| Female | −15.074 (−20.097, −10.050) | <0.001 | −16.466 (−23.286, −9.645) | <0.001 | −15.322 (−20.672, −9.971) | <0.001 | −12.546 (−16.795, −8.298) | <0.001 | −10.264 (−15.106, −5.422) | <0.001 | −12.334 (−16.938, −7.731) | <0.001 | −12.447 (−18.591, −6.303) | <0.001 | −9.522 (−13.515, −5.529) | <0.001 |
| Hypertension | 1.865 (−3.399, 7.129) | 0.487 | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| Anxiety | −2.478 (−9.327, 4.371) | 0.477 | — | — | — | — | — | — | −7.269 (−14.616, 0.077) | 0.052 | — | — | — | — | −3.250 (−8.716, 2.215) | 0.243 |
| Depression | — | — | — | — | — | — | — | — | −3.589 (−13.639, 6.461) | 0.483 | — | — | — | — | — | — |
| Fibromyalgia/chronic fatigue | −25.666 (−39.481, −11.851) | <0.001 | −28.310 (−49.099, −7.520) | 0.008 | −26.975 (−41.962, −11.988) | <0.001 | −23.478 (−35.369, −15.586) | <0.001 | −23.370 (−36.646, −10.094) | 0.001 | −16.190 (−29.037, −3.343) | 0.014 | −26.531 (−45.175, −7.887) | 0.005 | −12.143 (−23.173, −1.113) | 0.031 |
| Obesity (BMI > 30 kg/m2) | −8.192 (−13.232, −3.152) | 0.002 | −15.430 (−22.521, −8.338) | <0.001 | −5.467 (−10.672, −0.263) | 0.040 | −2.902 (−7.109, 1.306) | 0.176 | −6.075 (−10.650, −1.500) | 0.009 | — | — | — | — | −2.278 (−6.087, 1.532) | 0.241 |
| Age | −0.281 (−0.557, −0.004) | 0.047 | −0.056 (−0.289, 0.177) | 0.638 | −0.069 (−0.238, 0.100) | 0.424 | 0.039 (−0.196, 0.274) | 0.744 | −0.088 (−0.239, 0.063) | 0.254 | 0.064 (−0.082, 0.209) | 0.390 | 0.219 (0.009, 0.429) | 0.041 | 0.084 (−0.040, 0.208) | 0.185 |
| Age-adjusted Charlson Comorbidity Index | −2.611 (−4.675, −0.547) | 0.013 | — | — | — | — | −1.996 (−3.768, −0.223) | 0.027 | — | — | — | — | — | — | — | — |
| Length of hospital stay | −0.239 (−0.623, 0.146) | 0.223 | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| Max FiO2 | −0.065 (−0.209, 0.079) | 0.376 | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| CRP on admission | — | — | — | — | — | — | — | — | 0.033 (0.003, 0.063) | 0.031 | — | — | — | — | — | — |
| Ferritin at admission | 0.001 (−0.005, 0.006) | 0.779 | — | — | 0.001 (−0.006, 0.006) | 0.998 | 0.002 (−0.003, 0.007) | 0.365 | 0.003 (−0.002, 0.008) | 0.276 | 0.002 (−0.003, 0.007) | 0.393 | — | — | 0.001 (−0.003, 0.005) | 0.654 |
| Max ferritin during admission | 0.000 (−0.005, 0.005) | 0.961 | — | — | −0.001 (−0.006, 0.004) | 0.756 | −0.003 (−0.007, 0.001) | 0.173 | −0.003 (−0.007, 0.002) | 0.200 | −0.003 (−0.007, 0.002) | 0.204 | — | — | 0.000 (−0.004, 0.003) | 0.825 |
| Model parameters | ||||||||||||||||
| R 2 | 0.271 | 0.111 | 0.133 | 0.157 | 0.155 | 0.089 | 0.059 | 0.101 | ||||||||
| F (p) | 14.457 (<0.001) | 15.090 (<0.001) | 11.046 (<0.001) | 11.468 (<0.001) | 8.740 (<0.001) | 8.492 (<0.001) | 11.065 (<0.001) | 6.967 (<0.001) | ||||||||
| Df | 11, 428 | 4, 481 | 6, 433 | 6, 433 | 9, 430 | 5,434 | 3, 482 | 7, 432 | ||||||||
| 1-β | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | ||||||||
BMI, Body mass index; CI, Confidence interval; CRP, C-reactive protein; ICU, Intensive care unit; SF-36, 36-item Short Form health survey; Df, Degree of freedom. “—”: not included in the multivariate study.
Values in bold have reached statistical significance.