Table 5.
Multivariate Logistic Analysis to Determine Associations Between NHR Subgroup Levels and MACE
| Model 1 | P | Model 2 | P | Model 3 | P | |
|---|---|---|---|---|---|---|
| OR (95% CI) | OR (95% CI) | OR (95% CI) | ||||
| NHR | 1.17 (1.11, 1.22) | <0.0001* | 1.21 (1.15, 1.27) | <0.0001* | 1.19 (1.12, 1.27) | <0.0001* |
| NHR Quartile | ||||||
| NHR≤5.29 | 1.0 | 1.0 | 1.0 | |||
| 5.29<NHR≤7.48 | 2.45 (1.30,4.61) | 0.0057* | 2.75 (1.43, 5.29) | 0.0023* | 3.31 (1.56, 7.03) | 0.0018* |
| 7.48<NHR≤10.49 | 1.99 (1.04, 3.80) | 0.0367* | 2.66 (1.36, 5.21) | 0.0044* | 2.45 (1.12, 5.37) | 0.0246* |
| 10.49<NHR | 6.17 (3.34,11.39) | <0.0001* | 9.56 (4.92, 18.58) | <0.0001* | 8.15 (3.63, 18.29) | <0.0001* |
| NHR for trend | 1.70 (1.41, 2.05) | <0.0001* | 1.97 (1.61, 2.42) | <0.0001* | 1.79 (1.40, 2.30) | <0.0001* |
Notes: Model 1: Non-adjusted. Model 2: adjust for: Male, Age. Model3: adjust for: Male, Age, Killip Class 2-4, Systolic pressure, Diastolic pressure, Heart rate, Smoke, Stroke, Diabetes, Hypertension, Gensini score, Platelet, FPG, BUN, sCr, UC, ALB, TG, LDL-C, LVEF, LVFS*P<0.05.
Abbreviations: OR, Odds ratio; CI, Confidence interval; NHR, Neutrophil to HDL-C ratio; MHR, Monocyte to HDL-C ratio; HDL-C, High-density lipoprotein cholesterol; MACE, Major adverse cardiovascular event; FPG, fasting plasma glucose; BUN, blood urea nitrogen; sCr, serum creatinine; UC, Uric acid; ALB, albumin; TG, triglyceride; HDL-C, High-density lipoprotein cholesterol; LDL-C, Low-density lipoprotein cholesterol; LVEF, left ventricular ejection fraction; LVFS, left ventricular fraction shortening.