Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Steatosis-Activity-Fibrosis (SAF) Score
| Grade | Steatosis | Ballooning degeneration | Lobular inflammation (LI) | Fibrosis |
|---|---|---|---|---|
| 0 | <5% | None | None | None |
| 1 | 5%–33% | Mild (non-classical) | 2 or fewer foci/lobules | Perisinusoidal or periportal |
| 2 | 34%–66% | Prominent (classic) | >2 foci/lobule | Perisinusoidal and portal/periportal |
| 3 | >66% | Bridging | ||
| 4 | Cirrhosis |
Mild BD (non-classical BD), hepatocyte size unchanged, but cell rounded; Prominent BD (classical BD), hepatocyte size increased at least twofold.
