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. 2023 Oct 20;18(10):e0291762. doi: 10.1371/journal.pone.0291762

Fig 6. Doenjang changes renal mRNA levels related to RAS in HD-induced obese rats.

Fig 6

(A) mRNA levels of RAS-related genes in the kidney. (B) Aldosterone releasing factors-related mRNA levels in the kidney. (C) The levels of Mr and Renalase mRNA in the kidney. Values are given as mean ± SEM (n = 6). Values with different superscripts are significantly different (p < 0.05) by ANOVA with Tukey’s post hoc test (a > b). Values with Asterisk present significant differences between the groups by unpaired t-test (*p < 0.05 and **p<0.01). ND; normal diet, HD; high-fat diet, HDS; high-fat diet with salt, and HDJ; high-fat diet with doenjang. Ace; Angiotensin-converting enzyme, Agtr1; Angiotensin II receptor type 1, Agtr2; Angiotensin II receptor type 2, Star; Steroidogenic Acute Regulatory Protein, Hsd3b1; 3β-hydroxysteroid dehydrogenase type 1, Cyp11a1; cholesterol side-chain cleavage enzyme, Cyp21; 21-hydroxylase, and Mr; Mineralocorticoid receptor.