Table 3. Baseline body mass composition and muscle physiology in the different genotypes split by sex.
| Women | Men | |||||
|---|---|---|---|---|---|---|
| DD | ID/II | P value | DD | ID/II | P value | |
| n | 21 | 51 | 23 | 35 | ||
| Weight (kg) | 62.87 ± 12.51 | 64.45 ± 10.56 | 0.780 | 82.00 (73.70, 90.05) | 80.20 (73.55, 88.50) | 0.937 |
| BMI (kg/m2) | 25.06 (21.87, 27.04) | 26.16 (24.09, 28.60) | 0.232 | 28.41 (26.09, 30.11) | 27.11 (25.27, 30.40) | 0.567 |
| Height (m) | 157 (154, 163) | 157 (152, 161) | 0.289 | 169 (167, 174) | 173 (167, 177) | 0.373 |
| muscle mass (kg/m2) | 5.59 (5.29, 6.00) | 5.79 (5.53, 5.98) | 0.295 | 7.43 (6.79, 7.62) | 7.17 (6.82, 7.79) | 0.855 |
| upper limb fat mass (kg) | 2.73 (2.23, 3.51) | 3.21 (2.26, 3.83) | 0.511 | 2.52 (2.03, 3.02) | 2.78 (2.28, 3.25) | 0.131 |
| lower limb fat mass (kg) | 8.51 (6.54, 10.02) | 9.79 (7.85, 12.07) | 0.043 | 6.45 (5.20, 8.11) | 6.74 (5.54, 8.89) | 0.666 |
| upper limb muscle mass (kg) | 3.41 (3.09, 3.79) | 3.35 (2.92, 3.80) | 0.511 | 5.66 (5.09, 6.49) | 5.96 (5.15, 6.53) | 0.435 |
| lower limb muscle mass (kg) | 10.76 ± 1.22 | 10.62 ± 1.78 | 0.712 | 16.00 ± 1.63 | 15.79 ± 2.91 | 0.749 |
| SPPB baseline | 7.0 (6.0, 9.0) | 7.0 (5.0, 9.0) | 0.975 | 8.0 (6.0, 9.0) | 7.0 (5.0, 9.0) | 0.315 |
| Grip strength baseline (kg) | 13.9 ± 3.6 | 13.5 ± 3.6 | 0.593 | 22.8 ± 4.1 | 22.1 ± 6.1 | 0.595 |
| QMVC baseline (kg) | 10.4 (7.1, 12.4) | 9.4 (6.6, 13.5) | 0.796 | 13.2 (10.5, 15.9) | 18.0 (14.5, 21.6) | 0.028 |
| QMVC/leg muscle mass (kg/kg) | 0.93 (0.67, 1.19 | 0.93 (0.65, 1.19) | 1.000 | 0.78 (0.63, 1.15) | 1.18 (0.86,1.33) | 0.035 |
BMI: body mass index, SPPB: Short Physical Performance Battery score: QMVC: Quadriceps Maximal Voluntary contraction. Normally distributed data are presented as mean ± SD with significance of differences determined by t-test. Non-parametric data are presented as median (inter quartile range) and the significance of differences was determined by Mann Whitney U test