Table 1.
Comparison of three ultrasound-enhancing agents approved for cardiac imaging.
| Ultrasound enhancing Agent | Shell | Core | Preparation requirements |
|---|---|---|---|
| Lumason | Phospholipid shell | Sulfur hexafluoride gas | Mixing and hand agitation |
| Optison | Human Serum albumin | Octafluoropropane (perflutren) gas | Resuspension of the bubbles by hand |
| Definity | Phospholipid shella | Octafluoropropane (perflutren) gas | Activation with mechanical agitation |
a
The phospholipid shell of Lumason and Definity, differ in lipid composition and charge.