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. Author manuscript; available in PMC: 2024 Oct 1.
Published in final edited form as: Gastroenterology. 2023 Jul 25;165(4):963–975.e5. doi: 10.1053/j.gastro.2023.06.036

Table 3.

Multivariable Analysis Showing Those Baseline Factors Independently Associated With Achievement of Deep Steroid-Free Remission at Week 14 (Infliximab and Vedolizumab) or Week 16 (Ustekinumab)

Baseline variable Adjusted OR 95% CI P value

Previous exposure to a biologic 3.49 1.43–8.53 <.01a
Age (OR per year) 1.01 1.04–0.97 .76
Visceral adipose tissue (OR per IA-VAT% of body mass) 0.40 0.16–0.98 .03a
Total body fat (OR per % of body mass) 0.97 0.92–0.98 .19
Baseline C-reactive protein (OR per mg/dL) 0.72 1.02–1.09 .03a
Baseline albumin (OR per g/dL) 0.58 0.05–6.71 .67
Drug level higher than the median within the populationbc 2.97 1.20–7.32 .02a
a

Statistically significant.

b

Stratified by each drug group: infliximab, vedolizumab, and ustekinumab.

c

Median drug levels were 9.8, 11.1, and 4.9 mg/dL for infliximab, vedolizumab, and ustekinumab, respectively.