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. 2023 May 3;94(4):1317–1326. doi: 10.1038/s41390-023-02610-5

Fig. 2. Examples of urinary metabolite abundance over time in HC-treated and control infants.

Fig. 2

a 17hydroxypregnanolone glucuronide in an infant treated with HC days 25–81 and receiving full oral feeds at day 44; b 17hydroxypregnanolone glucuronide in a control infant; c tigloylglycine, a metabolite of isoleucine, in a HC-treated infant days 24–52; d tigloylglycine in a control infant; e 6-sialyl-N-acetyllactosamine, an oligosaccharide, in a HC-treated infant days 14–48; f 6-sialyl-N-acetyllactosamine in a control infant. g Concentrations of erythronate and mevalonolactone in an infant receiving a 10-day course of HC; levels decrease on starting HC and increase 1.6- and 1.9-fold by off/on analysis on stopping HC. h Concentrations of erythronate and mevalonolactone remain lower until transitioning to oral feeds in an infant on HC days 25–81.