Table 4.
The mean relative abundances (%) of different bacterial groups connected to specific ASVs in the gut microbiota and the p-values of the comparisons to the double placebo group (ANCOM-BC).
| Group | Placebo | C-LGG + Bb12 | C-LGG | M-LGG + Bb12 | M-LGG | |
|---|---|---|---|---|---|---|
| Bifidobacterium animalis | ||||||
| Relative abundance (%) | 0 | 9.0a | 0.1b | 0.1 | 0b | |
| p-value, difference to the placebo group | – | <0.00010 | 1.0 | 1.0 | 1.0 | |
| Staphylococcus saprophyticus | ||||||
| Relative abundance (%) | 43.0 | 26.2c | 43.1 | 51.4 | 62.2c | |
| p-value, difference to the placebo group | – | 1.0 | 1.0 | 1.0 | 1.0 | |
| Lactobacillales (order) | ||||||
| Relative abundance (%) | 5.4 | 29.0d | 3.6d | 8.8 | 12.4 | |
| p-value, difference to the placebo group | – | 0.020 | 1.0 | 1.0 | 1.0 | |
| Streptococcus equi | ||||||
| Relative abundance (%) | 9.2 | 1.8 | 0 | 0 | 0 | |
| p-value, difference to the placebo group | – | 0.44 | 0.015 | 0.015 | 0.012 | |
The ASVs of which relative abundances were statistically different between intervention arms are described here described by the names of the bacterial groups they correspond.
aThere were also statistically significantly more Bifidobacterium animalis in the group C-LGG + Bb12 than in the groups C-LGG (p < 0.0001), M-LGG + Bb12 (p = 0.0079), and M-LGG (p < 0.0001).
bThere were statistically significantly more Bifidobacteria animalis in the group C-LGG than in the group M-LGG (p = 0.040).
cThere were statistically significantly more Staphylococcus saprophyticus in the group M-LGG than in the group C-LGG + Bb12 (p = 0.0072).
dThere were statistically significantly more ASVs associated with the order Lactobacillales in the group C-LGG + Bb12 than in the group C-LGG (p = 0.00050).