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. 2023 Oct 20;6(12):e202302073. doi: 10.26508/lsa.202302073

Figure 7. Expression of HH pathway members in E12.5 Tmem107−/− animals.

Figure 7.

(A, A’, A’’, B, B’, B’’) Immunostaining of WT embryos (A, A’, A’’) and Tmem107−/− (B, B’, B’’) revealed higher expression of SHH (red) protein in neural retina of Tmem107-deficient animals. (C, C’, C’’, D, D’, D’’) WT embryos (C, C’, C’’) exhibits revealed higher expression of Ptch1 (green) mRNA in lens and neural retina in Tmem107−/− (D, D’, D’’) as analyzed by RNAScope. Nuclei are counterstained with DAPI. Scale bar = 100 μm.