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. 2023 Oct 20;13:17924. doi: 10.1038/s41598-023-44400-3

Table 2.

Time-related differences in incidence of selected CVDs.

Overall distribution (regardless of sex, N = 8744)
Variable Class Year: 2019 Year: 2020 Year: 2019 Year: 2020 No stratification corrections Generalized CMH (adjusted for stratification by sex)
count (n) count (n) frequency (%) frequency (%) χ2 p OR OR {− 95% CI} OR {95% CI} χ2 p OR OR {− 95% CI} OR {95% CI}
ACS ACS 1530 (1496.24) 1414 (1447.76) 34.43 32.88 2.34 0.1265 1.76 0.1842
No ACS 2914 (2947.76) 2886 (2852.24) 65.57 67.12
Arrhythmia Arrhythmia 911 (9319) 921 (900.91) 20.50 21.42 1.11 0.2910 0.92 0.3385
No arrhythmia 3533 (3512.91) 3379 (3399.09) 79.50 78.58
PE PE 114 (131.12) 144 (126.88) 2.57 3.35 4.69 0.0304 1.316 1.026 1.689 4.47 0.0346 1.308 1.019 1.678
No PE 4330 (4312.88) 4156 (4173.12) 97.43 96.65
AHF AHF 527 (446.74) 352 (432.26) 11.86 8.19 32.60  < 0.00001 0.663 0.575 0.764 32.29  < 0.00001 0.664 0.576 0.765
No AHF 3917 (3997.26) 3948 (3867.74) 88.14 91.81
Other CVDs Other CVDs 1362 (1438.81) 1469 (1392.19) 30.65 34.16 12.33 0.0005 1.174 1.073 1.284 11.53 0.0007 1.169 1.068 1.278
ACS/arrhythmia/PE/AHF 3082 (3005.19) 2831 (2907.81) 69.35 65.84
Subset distribution (sex: female, N = 3333)
Variable Class Year: 2019 Year: 2020 Year: 2019 Year: 2020 χ2 p OR OR {− 95% CI} OR {95% CI}
Count (n) Count (n) Frequency (%) Frequency (%)
ACS ACS 454 (431.76) 415 (437.24) 27.42 24.75 3.08 0.0793
No ACS 1202 (1224.24) 1262 (1239.76) 72.58 75.25
Arrhythmia Arrhythmia 393 (398.47) 409 (403.53) 23.73 24.39 0.20 0.6573
No arrhythmia 1263 (1257.53) 1268 (1273.47) 76.27 75.61
PE PE 53 (60.12) 68 (60.88) 3.20 4.05 1.74 0.1873 1.278 0.887 1.843
No PE 1603 (1595.88) 1609 (1616.12) 96.80 95.95
AHF AHF 168 (155.51) 145 (157.49) 10.14 8.65 2.20 0.1381 0.838 0.664 1.059
No AHF 1488 (1500.49) 1532 (1519.51) 89.86 91.35
Other CVDs Other CVDs 588 (610.13) 640 (617.87) 35.51 38.16 2.53 0.1120 1.121 0.974 1.291
ACS/arrhythmia/PE/AHF 1068 (1045.87) 1037 (1059.13) 64.49 61.84
Subset distribution (sex: male, N = 5411)
Variable Class Year: 2019 Year: 2020 Year: 2019 Year: 2020 χ2 p OR OR {− 95% CI} OR {95% CI}
Count (n) Count (n) Frequency (%) Frequency (%)
ACS ACS 1076 (1069.14) 999 (1005.86) 38.59 38.09 0.15 0.7010
No ACS 1712 (1718.86) 1624 (1617.14) 61.41 61.91
Arrhythmia Arrhythmia 518 (530.7) 512 (499.3) 18.58 19.52 0.77 0.3787
No arrhythmia 2270 (2257.3) 2111 (2123.7) 81.42 80.48
PE PE 61 (70.59) 76 (66.41) 2.19 2.90 2.76 0.9684 1.334 0.948 1.876
No PE 2727 (2717.41) 2547 (2556.59) 97.81 97.10
AHF AHF 359 (291.63) 207 (274.37) 12.88 7.89 35.86  < 0.00001 0.580 0.484 0.694
No AHF 2429 (2496.37) 2416 (2348.63) 87.12 92.11
Other CVDs Other CVDs 774 (825.94) 829 (777.06) 27.76 31.61 9.57 0.0020 1.202 1.070 1.351
ACS/arrhythmia/PE/AHF 2014 (1962.06) 1794 (1845.94) 72.24 68.39

Numbers in ‘()’ brackets indicate expected (estimated) counts. Significant odds ratios (ORs) are marked in bold.