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. 2023 Oct 20;13:17924. doi: 10.1038/s41598-023-44400-3

Table 6.

Distribution of detailed CVD types in the context of SARS-Cov-test and sex.

Overall distribution (regardless of sex)
Variable Class SARS-Cov-2: negative SARS-Cov-2: positive SARS-Cov-2: negative SARS-Cov-2: positive No stratification corrections Generalized CMH (adjusted for stratification by sex)
Count (n) Count (n) Frequency (%) Frequency (%) χ2 p OR OR {− 95% CI} OR {95% CI} χ2 p OR OR {− 95% CI} OR {95% CI}
ACS: type NSTEMI 274 (280.51) 30 (23.49) 34.77 45.45 3.10 0.2120 3.67 0.1575
STEMI 410 (404.15) 28 (33.85) 52.03 42.42
Unstable angina 104 (103.34) 8 (8.66) 13.20 12.12
ACS: heart failure Symptoms present 116 (126.2) 21 (10.8) 15.76 33.33 12.61 0.0004 2.672 1.526 4.679 12.96 0.0003 2.708 1.546 4.743
No symptoms 620 (609.8) 42 (52.2) 84.24 66.67
Arrhythmia: type Atrial 145 (144.75) 13 (13.25) 49.15 48.15 0.08 0.7757 3.20 0.2016
Ventricular 41 (43.98) 7 (4.02) 13.90 25.93
Heart block, bradycardia 109 (106.27) 7 (9.73) 36.95 25.93
Arrhythmia: heart failure Symptoms present 75 (73.98) 4 (5.02) 28.30 22.22 0.31 0.5779 0.28 0.5949
No symptoms 190 (191.02) 14 (12.98) 71.70 77.78
PE: heart failure Symptoms present 9 (7.43) 2 (3.57) 36.00 16.67 0.67 0.4121 1.40 0.2368
No symptoms 16 (17.57) 10 (8.43) 64.00 83.33
AHF: type CHF decompensation 95 (95.78) 10 (9.22) 70.37 76.92 0.031 0.8594 0.40 0.5267
De novo 40 (39.22) 3 (3.78) 29.63 23.08
Subset distribution (sex: female)
Variable Class SARS-Cov-2: negative SARS-Cov-2: positive SARS-Cov-2: negative SARS-Cov-2: positive χ2 p OR OR {− 95% CI} OR {95% CI}
Count (n) Count (n) Frequency (%) Frequency (%)
ACS: type NSTEMI 106 (105.73) 6 (6.27) 41.90 40.00 0.88 0.6427
STEMI 111 (112.34) 8 (6.66) 43.87 53.33
Unstable angina 36 (34.93) 1 (2.07) 14.23 6.67
ACS: heart failure Symptoms present 42 (42.42) 3 (2.58) 18.26 21.43 0.00 0.9536 1.221 0.326 4.569
No symptoms 188 (187.58) 11 (11.42) 81.74 78.57
Arrhythmia: type Atrial 81 (80.76) 7 (7.24) 55.86 53.85 5.40 0.0672
Ventricular 15 (17.44) 4 (1.56) 10.34 30.77
Heart block, bradycardia 49 (46.8) 2 (4.2) 33.79 15.38
Arrhythmia: heart failure Symptoms present 28 (26.13) 0 (1.87) 22.22 0.00 1.35 0.2448
No symptoms 98 (99.87) 9 (7.13) 77.78 100.00
PE: heart failure Symptoms present 5 (4.0) 1 (2.0) 41.67 16.67 0.28 0.5959
No symptoms 7 (8.0) 5 (4.0) 58.33 83.33
AHF: type CHF decompensation 32 (31.5) 4 (4.5) 65.31 57.14  < 0.00001 1.0000
De novo 17 (17.5) 3 (2.5) 34.69 42.86
Subset distribution (sex: male)
Variable Class SARS-Cov-2: negative SARS-Cov-2: positive SARS-Cov-2: negative SARS-Cov-2: positive χ2 p OR OR {− 95% CI} OR {95% CI}
Count [n] Count [n] Frequency [%] Frequency [%]
ACS: type NSTEMI 168 (175.29) 24 (16.71) 31.40 47.06 5.90 0.0524
STEMI 299 (291.24) 20 (27.76) 55.89 39.22
Unstable angina 68 (68.47) 7 (6.53) 12.71 13.73
ACS: heart failure Symptoms present 74 (83.88) 18 (8.12) 14.62 36.73 15.79 0.0001 3.390 1.804 6.371
No symptoms 432 (422.12) 31 (40.88) 85.38 63.27
Arrhythmia: type Atrial 64 (64.02) 6 (5.98) 42.67 42.86 0.18 0.9135
Ventricular 26 (26.52) 3 (2.48) 17.33 21.43
Heart block, bradycardia 60 (59.45) 5 (5.55) 40.00 35.71
Arrhythmia: heart failure Symptoms present 47 (47.9) 4 (3.1) 33.81 44.44 0.083 0.7729
No symptoms 92 (91.1) 5 (5.9) 66.19 55.56
PE: heart failure Symptoms present 4 (3.42) 1 (1.58) 30.77 16.67 0.0078 0.9245
No symptoms 9 (9.58) 5 (4.42) 69.23 83.33
AHF: type CHF decompensation 63 (64.5) 6 (4.5) 73.26 100.00 0.95 0.3295
De novo 23 (21.5) 0 (1.5) 26.74 0.00

Numbers in ‘()’ brackets indicate expected (estimated) counts. Significant odds ratios (ORs) are marked in bold.