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. 2023 Oct 20;3:151. doi: 10.1038/s43856-023-00376-9

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Humoral IgG responses of urban (n = 80) and indigenous children (n = 82) towards the spike S1 subdomain of OC43 (a), HKU1 (b), NL63 (c), and 229E (d) are split based on SARS-CoV-2 serostatus. Box and whisker plots represent the median, 25th and 75th percentiles. Whiskers show the largest and smallest non-outliers values. Outliers were identified using upper/lower quartile 1.5 ± times IQR. Statistical significance was defined as p < 0.05 using the Wilcoxon’s ranked sum test.