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. 2023 Oct 20;9:85. doi: 10.1038/s41523-023-00588-1

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A The correlation between the expression level of TRIM21 and relapse-free survival of breast cancer and basal-like breast cancer, respectively. B Colony formation assay and C CTG assay were performed to detect the proliferation capability of TRIM21^KO and TRIM21^OE TNBC cells. D The migration abilities were measured by wound-healing assay. The quantitative wound-healing trends obtained from wound size were illustrated. E The invasion abilities were indicated by transwell assay and presented as photofluorograms through DAPI staining. Data are shown as the mean ± SD of at least three independent experiments. Bar length: 100 μm. The significant level was identified by *P < 0.05, **P < 0.01, ***P < 0.001 and ****P < 0.0001 by one-way ANOVA.