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. 2023 Oct 20;7:106. doi: 10.1038/s41698-023-00457-x

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Number of variants (3x consensus) for each of the cases as well as sensitivity and positive predictive value for each of the cases and institutions. Empty boxes (case 29) = no variants detected. b Sensitivity and positive predictive value for each of five institutions in comparison to three different references: consensus list of variants found in at least two institutions (Consensus 2x, triangle), consensus of variants found in at least three institutions (Consensus 3x, square), and TSO500 (circle). c Inter-institution concordance of therapeutic relevant somatic variants (OncoKB levels 1–4) with associated treatments and their OncoKB level. Boxes indicate detected variants and are colored by treatment option, variants marked with “SV” were found as structural variant.