Figure 1.

Associations of continuous risk factors with cardiovascular disease and all-cause mortality allowing for non-linear effects. Global analyses.

Individuals with cardiovascular disease at baseline were excluded. Age was used as the time scale. All five risk factors considered were included in the models together with use of antihypertensive medications. A one-year landmark analysis was performed. Confidence interval widths have not been adjusted for multiplicity and should not be used in place of hypothesis testing. To convert the values for non-HDL cholesterol from milligrams per deciliter (mg/dL) to millimoles per liter (mmol/L), multiply by 0.02586.