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. Author manuscript; available in PMC: 2023 Oct 21.
Published in final edited form as: N Engl J Med. 2023 Aug 26;389(14):1273–1285. doi: 10.1056/NEJMoa2206916

Figure 2.

Figure 2.

Associations of risk factors with cardiovascular disease and all-cause mortality allowing for effects to change with age. Global analyses.

Individuals with cardiovascular disease at baseline were excluded. Age was used as the time scale. All five risk factors considered were included in the models together with use of antihypertensive medications. A one-year landmark analysis was performed. Global estimates are presented. Confidence interval widths have not been adjusted for multiplicity and should not be used in place of hypothesis testing. To convert the values for non-HDL cholesterol from milligrams per deciliter (mg/dL) to millimoles per liter (mmol/L), multiply by 0.02586.