Table 3.
In vivo in NMRI mice.
| Classification | Compound/Extract | Source | Dose; Duration | Efficacy | Mechanism | Reference |
|---|---|---|---|---|---|---|
| Plant | Hydro-alcoholic Licorice extract | Glycyrrhiza glabra | 100, 150 mg/kg/day; 3 weeks | Protective effects on PCOS | ↓ovarian cyst | [17] |
| Decoction | Lutein and nettle extract | Urtica dioica(nettle) | (1) 200, 400 mg/kg (2) 125, 250 mg/kg (3) Combination 200 & 125 mg/kg; 30 days |
Improvement of reproductive function | ↑TAC ↓MDA |
[32] |
| Decoction | Combination of Paeonia spp. and Glycyrrhiza glabra |
Paeonia spp., Glycyrrhiza glabra |
50, 100 mg/kg/day; 20 days | Synergistic effects on polycystic ovary | Improvement of follicles in the ovaries | [33] |
TAC, total antioxidant capacity; MDA, malondialdehyde; ↑, up-regulation; ↓, down-regulation.