FIG. 7.

Effect of AmB pretreatment on conidial killing determined by colony counting. MDMs were preincubated with AmB at the indicated concentrations and washed; the conidia were then added. Twelve hours after phagocytic uptake, reisolated conidia were plated on Sabouraud agar and colonies were enumerated after 2 to 3 days. By comparison with the controls, which were incubated for only 45 min, a KI (y axis) was calculated for each sample. A dose-dependent increase in conidial killing was observed in AmB-pretreated MDMs (mean ± standard deviation; n = 5).