Comparison 2. Antifibrinolytics versus control (TBI patients).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 All‐cause mortality	2	510	Risk Ratio (M‐H, Fixed, 95% CI)	0.63 [0.40, 0.99]
2 Myocardial infarction	2	510	Risk Ratio (M‐H, Fixed, 95% CI)	0.51 [0.09, 2.73]
3 Stroke	2	510	Risk Ratio (M‐H, Fixed, 95% CI)	0.34 [0.01, 8.35]
4 Deep vein thrombosis	2	510	Risk Ratio (M‐H, Fixed, 95% CI)	0.25 [0.03, 2.26]
5 Pulmonary embolism	2	510	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
6 Surgical intervention	2	510	Risk Ratio (M‐H, Fixed, 95% CI)	1.12 [0.65, 1.93]
7 Blood transfusion	2	510	Risk Ratio (M‐H, Fixed, 95% CI)	0.86 [0.66, 1.12]
8 Progressive intracranial haemorrhage	2	478	Risk Ratio (M‐H, Fixed, 95% CI)	0.75 [0.58, 0.98]
9 New brain lesions	1		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected
10 Poor outcome (death or disability)	2	510	Risk Ratio (M‐H, Fixed, 95% CI)	0.77 [0.58, 1.02]