Table 2.
Multivariable cox regression analysis for 1-year and long-term all-cause mortality
| Groups | MIMIC-IV | CIN-II | ||||
|---|---|---|---|---|---|---|
| Events (rate, %) | HR (95%CI) | P value | Events (rate, %) | HR (95%CI) | P value | |
| 1-year all-cause mortality | ||||||
| SHR (continuous) | 381 (17.6) | 1.30 (1.19–1.42) | < 0.001 | 298 (13.7) | 1.34 (1.01–1.78) | 0.043 |
| SHR (categorical) | ||||||
| Quartile 1 | 79 (14.6) | 1.22 (0.88–1.68) | 0.239 | 71 (13.1) | 1.14 (0.80–1.64) | 0.459 |
| Quartile 2 | 70 (12.9) | Ref | 55 (10.1) | Ref | ||
| Quartile 3 | 85 (15.7) | 1.30 (0.94–1.78) | 0.110 | 74 (13.7) | 1.27 (0.89–1.81) | 0.191 |
| Quartile 4 | 147 (27.1) | 1.87 (1.40–2.50) | < 0.001 | 98 (18.0) | 1.44 (1.03–2.02) | 0.034 |
| Long-term all-cause mortality# | ||||||
| SHR (continuous) | 511 (23.6) | 1.30 (1.19–1.41) | < 0.001 | 632 (29.1) | 1.26 (1.01–1.57) | 0.038 |
| SHR (categorical) | ||||||
| Quartile 1 | 120 (22.1) | 1.21 (0.92–1.57) | 0.170 | 170 (31.3) | 1.11 (0.88–1.41) | 0.364 |
| Quartile 2 | 103 (19.0) | Ref | 133 (24.5) | Ref | ||
| Quartile 3 | 110 (20.4) | 1.23 (0.94–1.61) | 0.140 | 145 (26.8) | 1.04 (0.82–1.33) | 0.735 |
| Quartile 4 | 178 (32.8) | 1.63 (1.27–2.09) | < 0.001 | 184 (33.9) | 1.32 (1.05–1.66) | 0.017 |
Both cohorts adjusted for age, gender, hypertension, diabetes mellitus, congestive heart failure, chronic kidney disease, atrial fibrillation, stroke, anemia, and revascularization;
#: Maximum follow-up of 12.1 years for American MIMIC-IV cohort, and 14.1 years for Chinese CIN-II cohort