Table 1.
Baseline characteristics of patients stratified by the TyG index tertiles
| Variable | T1 (n = 210) | T2 (n = 211) | T3 (n = 212) | P value |
|---|---|---|---|---|
| Age, years | 70.28 ± 10.53 | 67.50 ± 10.46 | 66.31 ± 10.91 | < 0.001 |
| Female, n (%) | 67 (31.9) | 71 (33.6) | 70 (33.0) | 0.928 |
| BMI, kg/m2 | 24.24 ± 2.93 | 24.99 ± 2.85 | 25.45 ± 3.40 | < 0.001 |
| Smoking, n (%) | 90 (42.9) | 95 (45.0) | 99 (46.7) | 0.729 |
| Previous PCI, n (%) | 28 (13.3) | 16 (7.6) | 24 (11.3) | 0.154 |
| COPD, n (%) | 11 (5.2) | 8 (3.8) | 9 (4.2) | 0.762 |
| Hypertension, n (%) | 156 (74.3) | 165 (78.2) | 156 (73.6) | 0.495 |
| AF, n (%) | 19 (9.0) | 13 (6.2) | 20 (9.4) | 0.408 |
| Previous stroke, n (%) | 15 (7.1) | 8 (3.8) | 13 (6.1) | 0.313 |
| SBP, mmHg | 133.19 ± 21.80 | 134.00 ± 22.87 | 134.79 ± 21.21 | 0.459 |
| HR, bpm | 77.51 ± 13.86 | 77.36 ± 14.72 | 81.45 ± 15.72 | 0.006 |
| cTnT, pg/mL | 25.90 (13.80, 550.40) | 28.66 (13.00, 502.10) | 49.17 (14.00, 459.30) | 0.388 |
| BNP, pg/mL | 97.90 (40.55, 304.25) | 99.60 (34.70, 328.80) | 137.18 (45.93, 485.15) | 0.132 |
| Scr, µmol/L | 79.85 (66.70, 98.35) | 76.00 (64.00, 92.70) | 78.55 (63.03, 101.20) | 0.248 |
| Uric acid, µmol/L | 369.76 ± 117.54 | 386.24 ± 125.92 | 379.99 ± 127.59 | 0.387 |
| FBG, mmol/L | 6.70 ± 2.06 | 8.38 ± 2.49 | 10.28 ± 3.85 | < 0.001 |
| HbA1c | 7.00 ± 1.40 | 7.74 ± 1.78 | 8.04 ± 1.78 | < 0.001 |
| TG, mmol/L | 1.01 ± 0.29 | 1.38 ± 0.39 | 2.22 ± 0.99 | < 0.001 |
| TC, mmol/L | 3.98 ± 1.13 | 4.40 ± 1.28 | 4.78 ± 1.27 | < 0.001 |
| HDL-C, mmol/L | 1.17 ± 0.30 | 1.09 ± 0.28 | 1.12 ± 0.30 | 0.012 |
| LDL-C, mmol/L | 2.37 ± 0.78 | 2.68 ± 0.89 | 2.93 ± 0.90 | < 0.001 |
| LVEF | 55.01 ± 9.39 | 55.43 ± 9.37 | 53.28 ± 10.23 | 0.053 |
| AMI, n (%) | 89 (42.4) | 89 (42.2) | 106 (50.0) | 0.183 |
| Diagnosis, n (%) | 0.429 | |||
| CCS | 33 (15.7) | 35 (16.6) | 22 (10.4) | |
| UA | 88 (41.9) | 87 (41.2) | 84 (39.6) | |
| NSTEMI | 48 (22.9) | 43 (20.4) | 53 (25.0) | |
| STEMI | 41 (19.5) | 46 (21.8) | 53 (25.0) | |
| Aspirin, n (%) | 204 (97.1) | 206 (97.6) | 203 (95.3) | 0.519 |
| P2Y12 receptor inhibitor, n (%) | 208 (99.0) | 210 (99.5) | 208 (98.1) | 0.368 |
| Statins, n (%) | 203 (96.7) | 206 (97.6) | 209 (98.6) | 0.432 |
| β-Blockers, n (%) | 145 (69.0) | 145 (68.7) | 162 (76.4) | 0.141 |
| ACEI/ARB, n (%) | 100 (47.6) | 108 (51.2) | 112 (52.8) | 0.550 |
| Diuretics, n (%) | 39 (18.6) | 47 (22.3) | 53 (25.0) | 0.278 |
| Insulin, n (%) | 45 (21.4) | 62 (29.4) | 60 (28.3) | 0.133 |
| Oral hypoglycemic agents, n (%) | 145 (69.0) | 156 (73.9) | 149 (70.3) | 0.516 |
| MVD, n (%) | 151 (71.9) | 154 (73.0) | 168 (79.2) | 0.172 |
| LM, n (%) | 11 (5.2) | 24 (11.4) | 10 (4.7) | 0.013 |
| Calcified lesions, n (%) | 38 (18.1) | 39 (18.5) | 42 (19.8) | 0.894 |
| Thrombosis, n (%) | 19 (9.0) | 16 (7.6) | 23 (10.8) | 0.507 |
| Long lesion, n (%) | 125 (59.9) | 130 (61.6) | 141 (66.5) | 0.314 |
| CTO, n (%) | 41 (19.5) | 39 (18.5) | 59 (27.8) | 0.039 |
| Number of stents | 1.51 ± 0.92 | 1.51 ± 0.94 | 1.58 ± 0.96 | 0.643 |
| Length of stents, mm | 39.18 ± 26.43 | 40.05 ± 28.58 | 43.20 ± 29.07 | 0.301 |
| TyG index | 8.50 ± 0.32 | 9.05 ± 0.13 | 9.67 ± 0.38 | < 0.001 |
| bSS | 14.00 (8.00, 21.00) | 16.00 (9.00, 21.50) | 15.75 (10.00, 21.38) | 0.379 |
| rSS | 3.00 (0.00, 8.00) | 5.00 (0.00, 9.00) | 4.00 (1.00, 9.00) | 0.286 |
Data are presented as mean ± SD, median (IQR) or n (%)
BMI body mass index, PCI percutaneous coronary intervention, COPD chronic obstructive pulmonary disease, AF atrial fibrillation, SBP systolic blood pressure, HR heart rate, BNP brain natriuretic peptide, Scr serum creatinine, FBG fasting blood glucose, TG triglyceride, TC total cholesterol, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol, LVEF left ventricular ejection fraction, AMI acute myocardial infarction, CCS chronic coronary syndrome, UA unstable angina, STEMI ST-segment elevation myocardial infarction, NSTEMI non-ST-segment elevation myocardial infarction, ACEI/ARB angiotensin converting enzyme inhibitor/angiotensin receptor blocker, MVD multivessel disease, LM left main disease, CTO chronic total occlusion, TyG index the triglyceride-glucose index, bSS baseline SYNTAX score, rSS residual SYNTAX score, T1 TyG index < 8.85, T2 8.85 ≤ TyG index < 9.28, T3 TyG index ≥ 9.28