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. 2023 Jul 8;38(5):787–800. doi: 10.1016/j.virs.2023.07.003

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© 2023 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 7 — Structure docking model of nanobodies bound to RBDs. Crystal structure of SARS-CoV-2 RBD proteins were applied in structural modeling with aVHH-13, energy minimization and energy minimized were then conducted. A Structural analysis of the combination of aVHH-13 and SASR-CoV-2 prototype-RBD. RBD is colored in green and aVHH-13 is colored in cyan (same color annotation below). B Structural analysis of the combination of aVHH-13 and SASR-CoV-2 Delta-RBD. C Structural analysis of the combination of aVHH-13 and SASR-CoV-2 Omicron BA.1-RBD. D Structural analysis of the combination of aVHH-13 and SASR-CoV-2 Omicron BA.2-RBD.