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. 2023 Oct 14;9(10):e21056. doi: 10.1016/j.heliyon.2023.e21056

Table 2.

Analyzes of prognostic parameters in patients with esophageal squamous cell carcinoma.

variable Factors of layered HR (95%CI) p
Univariate analysis (Kaplan-meier analysis and the log-rank test)
TNM stage Ⅰ/Ⅱ/Ⅲ <0.001
Cell differentiation well/moderate/poor 0.025
Lymph node metastasis N0/N1–N2 <0.001
Tumour invasion depth T1/T2/T3 <0.001
Sex male/female 0.374
Age (y) <60/≥60 0.631
HOXC10 mRNA
low/high expression

<0.001
Multivariate analysis (COX regression analysis)
HR (95%CI)

TNM stage Ⅰ/Ⅱ/Ⅲ 6.368(2.298–17.641) <0.001
Cell differentiation well/moderate/poor 2.291(1.460–3.597) <0.001
HOXC10 mRNA high/lower expression 0.554(0.312–0.982) 0.043

HR, hazard ratio; CI, confidence interval.