. 1998 Oct;42(10):2633–2636. doi: 10.1128/aac.42.10.2633

TABLE 3.

In vitro activities of five antimicrobial agents against the 244 nasopharyngeal isolates of S. pneumoniae by E test^a

Antimicrobial agent	Penicillin-susceptible strains (n = 209)^b					Penicillin-intermediate and -resistant strains (n = 35)^c
Antimicrobial agent	R (%)	I (%)	MIC₅₀	MIC₉₀	MIC range	R (%)	I (%)	MIC₅₀	MIC₉₀	MIC range
Amoxicillin-clavulanate	0	0	0.016	0.023	0.016–0.125	5.7	2.9	0.023	0.125	0.016–4
Cefuroxime	0	0	0.032	0.125	0.016–0.38	8.6	2.9	0.19	0.75	0.064–6
Cefotaxime	0	0	0.016	0.032	0.004–0.19	2.9	5.7	0.064	0.125	0.023–1.5
Ceftriaxone	0	0	0.016	0.047	0.003–0.19	2.9	5.7	0.064	0.125	0.023–1.5
TMP-SMZ	62.4	11.9	3	32	0.016–32	65.7	22.9	4	32	0.094–32

All MICs given are in micrograms per milliliter. R, resistant strains; I, intermediate strains.

Susceptible, MIC ≤ 0.064 μg/ml.

Intermediate, MIC = 0.125 to 1 μg/ml; resistant, MIC ≥ 2 μg/ml.