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. 2023 Oct 23;2023(10):CD015252. doi: 10.1002/14651858.CD015252.pub2

3. Sensitivity analyses.

Outcome Main analysis result (95% CI) Sensitivity analysis Sensitivity analysis result (95% CI)
Adenoidectomy (with or without myringotomy) versus no treatment/watchful waiting
1.3.1 Persistence of OME up to 3 months RR 0.83 (0.61 to 1.13) Exclusion of studies with concerns over trustworthiness RR 0.68 (0.45 to 1.04)
1.3.1 Persistence of OME up to 3 months RR 0.83 (0.61 to 1.13) Fixed‐effect model RR 0.82 (0.65 to 1.03)
1.3.2 Persistence of OME up to 12 months RR 0.65 (0.36 to 1.15) Exclusion of studies with concerns over trustworthiness RR 0.60 (0.23 to 1.56)
1.3.2 Persistence of OME up to 12 months RR 0.65 (0.36 to 1.15) Fixed‐effect model RR 0.65 (0.36 to 1.15)
1.3.3 Persistence of OME over 12 months RR 0.90 (0.81 to 1.00) Exclusion of studies with concerns over trustworthiness RR 0.90 (0.82 to 1.00)
1.3.3 Persistence of OME over 12 months RR 0.90 (0.81 to 1.00) Exclusion of studies at high risk of bias RR 0.76 (0.47 to 1.22)
1.3.3 Persistence of OME over 12 months RR 0.90 (0.81 to 1.00) Fixed‐effect model RR 0.88 (0.78 to 0.99)
Adenoidectomy and bilateral ventilation tubes versus bilateral ventilation tubes only
2.2.1 Hearing threshold up to 3 months MD ‐0.79 (‐1.99 to 0.41) Exclusion of studies with concerns over trustworthiness MD ‐0.80 (‐2.49 to 0.89)
2.2.1 Hearing threshold up to 3 months MD ‐0.79 (‐1.99 to 0.41) Fixed‐effect model MD ‐0.79 (‐1.99 to 0.41)
2.2.1 Hearing threshold up to 12 months MD ‐2.18 (‐5.25 to 0.88) Exclusion of studies with concerns over trustworthiness MD ‐3.90 (‐6.34 to ‐1.46)
2.2.1 Hearing threshold up to 12 months MD ‐2.18 (‐5.25 to 0.88) Fixed‐effect model MD ‐1.66 (‐2.97 to ‐0.35)
2.3.2 Persistence of OME up to 12 months RR 0.81 (0.63 to 1.05) Fixed‐effect model RR 0.81 (0.65 to 1.00)
Adenoidectomy and unilateral ventilation tubes versus unilateral ventilation tubes only
3.2.1 Hearing threshold up to 12 months MD ‐5.36 (‐10.16 to ‐0.56) Fixed‐effect model MD ‐5.45 (‐9.03 to ‐1.86)
3.3.2 Presence or persistence of OME up to 12 months RR 0.57 (0.38 to 0.86) Fixed‐effect model RR 0.55 (0.42 to 0.72)

CI confidence interval; MD mean difference; RR risk ratio