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Pharmacodynamic indices (means ± standard deviations) of gatifloxacin in CSF after single-dose therapy
| Dose (mg/kg), n | T > MBC (h) | AUC/MBC ratio | Cpeak/MBC ratio |
|---|---|---|---|
| 7.5, 8 | 4.2 ± 1.7 | 12.2 ± 5.0 | 1.8 ± 0.3 |
| 15, 8 | 7.6 ± 1.9 | 22.1 ± 5.6 | 3.8 ± 0.6 |
| 30, 7 | 14.1 ± 6.7 | 68.5 ± 32.1 | 7.0 ± 1.9 |
