TABLE 1.

Distribution of intraocular pressure in naïve, PBS, RCI001, DEX-1, and DEX2 groups for 5 weeks after drug application.

	IOP (mmHg, mean ± SD)
	Week 0	Week 1	Week 2	Week 3	Week 4	Week 5
Naïve	10.1 ± 0.1	10.0 ± 0.0	10.0 ± 0.0	10.0 ± 0.0	10.1 ± 0.1	10.6 ± 0.3
PBS	10.3 ± 0.2	10.0 ± 0.0	10.1 ± 0.1	10.0 ± 0.0	10.1 ± 0.1	10.9 ± 0.3
RCI001	10.4 ± 0.2	10.0 ± 0.0	10.1 ± 0.1	10.0 ± 0.0	10.9 ± 0.5	10.9 ± 0.3
DEX-1	10.5 ± 0.2	10.4 ± 0.2	10.2 ± 0.2	10.4 ± 0.4	13.3 ± 0.8 *	14.5 ± 0.6 **
DEX-2	10.6 ± 0.4	11.1 ± 0.6	11.1 ± 0.6	11.0 ± 0.4	12.1 ± 0.5	14.6 ± 0.5 *

*P < 0.05; **P < 0.01 (comparison with baseline).

The bold values are significantly elevated values compared with baseline values.

IOP, intraocular pressure; PBS, phosphate-buffered saline; DEX-1, eye drops of 0.1% dexamethasone; DEX-2, subconjunctival injection of 0.1% dexamethasone.