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(A) Turbo spin echo (TSE) scans from randomly selected younger (top) and older (bottom) participants. (B) Sagittal view of TSE template (green) overlaid onto whole-brain template, both warped to MNI152 0.5mm (linear) space. (C) Detailed axial view of TSE template, warped to MNI152 space. (D) TSE template, warped to MNI152 space, overlaid with locus coeruleus meta-mask and pontine reference region from Dahl et al. (2022), which were used for calculation of LC contrast ratios.
