Antibodies |
PE anti-CD45 |
BioLegend |
Cat#103105 |
APC anti-CD31 |
Invitrogen |
Cat#17-0311-80 |
eFluor 450-conjugated Lineage (Lin) antibodies anti-CD45 |
ThermoFisher Scientific |
Cat#48-0451-82 |
anti-Ter-119 |
ThermoFisher Scientific |
Cat#48-5921-82 |
anti-CD31 |
BioLegend |
Cat#303114 |
anti-Tie-2 |
ThermoFisher Scientific |
Cat#13-5987-82 |
anti-CD326 |
ThermoFisher Scientific |
Cat#48-5791-82 |
anti-CD324 |
ThermoFisher Scientific |
Cat#13-3249-82 |
anti-CFH primary antibody |
LS bio |
Cat#LS-C819285 |
Alexa Fluor 488 anti-rabbit secondary antibody |
Invitrogen |
Cat#A-11008 |
CXCR2 antagonist AZ 10397767 |
Tocris |
Cat#5872 |
Critical commercial assays |
SMART-Seq v4 Ultra Low Input Kit |
Takara Bio |
Cat#634894 |
KAPA Hyper Prep Next Generation Sequencing |
Roche |
N/A |
miRNeasy Micro Kit |
QIAGEN |
Cat#217084 |
Fibroblast culture media (DMEM + Glutamax media) |
ThermoFisher |
Cat#10569010 |
Deposited data |
Raw RNAseq data |
This paper |
NCBI Sequence Read Archive; BioProject PRJNA839777 |
Raw scRNAseq data |
This paper |
NCBI Sequence Read Archive; BioProject PRJNA839777 |
Allele-specific count data (MRLxCAST) |
This paper; Figshare |
doi: https://doi.org/10.6084/m9.figshare.19952513.v1
|
CAST/EiJ SNP calls |
Wellcome Trust Mouse Genome Project |
https://www.sanger.ac.uk/science/data/mouse-genomes-project
|
Ear closure QTL mapping data |
Cheverud et al.6
|
N/A |
Mouse genome (GRCm38) |
Ensembl |
http://ensembl.org/
|
Experimental models: Organisms/strains |
Mouse: CAST/EiJ |
The Jackson Laboratory |
Strain #:000928 |
Mouse: MRL/MpJ |
The Jackson Laboratory |
Strain #:000486 |
Mouse: C57BL/6J |
The Jackson Laboratory |
Strain #:000664 |
Software and algorithms |
Bowtie2 |
Langmead and Salzberg58
|
http://bowtie-bio.sourceforge.net/bowtie2/index.shtml
|
DESeq2 |
Love et al.64
|
https://bioconductor.org/packages/release/bioc/html/DESeq2.html
|
DESeq2 analysis code |
This paper; Figshare |
doi: https://doi.org/10.6084/m9.figshare.c.6025157
|
Cutadapt |
Martin 201162
|
https://cutadapt.readthedocs.io/
|
Genome Analysis Toolkit (GATK) |
McKenna et al.60
|
https://gatk.broadinstitute.org/
|
BEDTools |
Quinlan and Hall66
|
https://bedtools.readthedocs.io/
|
Seurat |
Satija et al.69
|
https://satijalab.org/seurat/
|
scProportionTest |
Miller et al.72
|
https://github.com/rpolicastro/scProportionTest
|
CellChat |
Jin et al.73
|
http://www.cellchat.org/
|
Enrichr |
Chen et al.71
|
https://maayanlab.cloud/Enrichr/
|
PANTHER |
Mi et al.67
|
https://pantherdb.org
|
modPhea |
Weng and Liao68
|
https://evol.nhri.org.tw
|
Fiber quantification pipeline |
Mascharak et al.19
|
https://github.com/shamikmascharak/Mascharak-et-al-ENF
|
Other |
Supplemental figures and tables |
This paper; Mendeley Data |
doi: 10.17632/9jhfh79b8d.1
|