. Author manuscript; available in PMC: 2024 Nov 1.

Published in final edited form as: Trends Neurosci. 2023 Sep 19;46(11):941–952. doi: 10.1016/j.tins.2023.08.007

Table-1:

List of PET reporter systems.

Reporter system	Reporter gene(s)	Reporter probe(s)
Intracellular entrapment:	HSV-1 TK HSV-1-sr39TK hΔTK2 hDTK2 hdCK VZV-tk	[¹⁸F]FIAU, [¹⁸F]FMAU, [¹⁸F]FEAU, [¹⁸F]FHBG
	Pyruvate Kinase M2 (PKM2)	[¹⁸F]DASA-23
	AADC TH/GAD1	6-[¹⁸F]fluoro-L-m-tyrosine, [¹¹C]raclopride
Protein binding:	hSSTR2	[⁶⁸Ga]DOTATOC, [⁶⁸Ga]DOTATATE
	hD2R	[¹¹C]raclopride, [¹⁸F]fallypride, [¹⁸F]spiperone derivative.
	Cannabinoid (CB2) receptor	[¹¹C]GW405833
	ecDHFR	[¹⁸F]FE-TMP
	Optogenetics - ChRERa	[¹⁸F]FES
	Chemogenetics - DREADDs	[¹¹C]CLZ, [¹¹C]DCZ, and [¹⁸F]JHU37107
	Chemogenetics - PSAMs	[¹⁸F]ASEM
Transporter-based:	hNIS	[¹⁸F]tetrafluoroborate, [¹⁸F]fluorosulfate.
	hNET	[¹¹C]ephedrine, [¹²⁴I]meta-iodobenzylguanidine (MIBG), and [¹⁸F]meta-fluorobenzylguanidine (MFBG), [¹¹C]MeNER, and [¹¹C]MRB
	hSERT	[¹¹C]DASB, [¹¹C]McN 5652, [¹¹C]ADAM, [¹¹C]DAPA, and [¹¹C]AFM.