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. Author manuscript; available in PMC: 2024 Oct 1.
Published in final edited form as: Endocr Pract. 2023 Aug 6;29(10):787–793. doi: 10.1016/j.eprac.2023.07.031

Table 4.

Faculty member and trainee responses to clinical scenarios

Clinical scenario
Patient characteristics 1 2 3 4 5 6 7 8 9
 Sex Female Female Female Female Female Female Female Female Female
 Age (years) 31 31 31 31 31 31 72 72 72
 Current TSH level (mIU/L) 7.0 7.0 7.0 7.0 12.1 7.0 7.0 12.1 7.0
 Current FT4 level (ng/dL) 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.2
 Prior TSH level 3.6 6.8 6.8 6.8 10.4 6.8 6.8 10.4 6.8
 Desire for fertility No No Yes No No No NA NA NA
 Weight gain, depressed mood No No No Yes No No No No No
 History of HTN and obesity No No No No No Yes No No Yes
Participant responses (%)
No further treatment or monitoring 5.7 11.4 2.6 1.6 2.6 5.8 18.8 4.1 8.2
Monitor for symptoms, recheck TSH annually* 26.4 52.8 19.3 7.3 12.0 36.6 61.3 17.1 48.5
Re-check TSH and FT4 in 1–2 months 51.8 9.3 11.5 8.8 8.3 12.6 7.9 16.1 11.9
Check anti-TPO antibodies and start LT4 if positive 13.0 18.1 15.1 15.5 14.6 17.8 7.3 10.9 11.3
Begin treatment with LT4 3.1 8.3 51.6 66.8 62.5 27.2 4.7 51.8 20.1
*

For clinical scenario 3, response was modified to recheck TSH during first trimester of pregnancy. All TSH levels are in mIU/L. Provided reference ranges: TSH: 0.4 – 4.4 mIU/L; FT4: 0.9 – 1.7 ng/dL. Abbreviations: TSH: thyroid stimulating hormone; FT4: free T4; HTN: hypertension; TPO: thyroid peroxidase; LT4: levothyroxine.