TABLE 2.

In vitro antiviral activity of pleconaril against selected picornaviral clinical isolates (11)

Virus type (no. of clinical isolates tested)	IC50 (μg/ml)
	Median	Range
Coxsackievirus A9 (14)	0.006	0.002–0.058
Coxsackievirus B1 (13)	0.006	0.003–0.017
Coxsackievirus B2 (14)	0.005	0.002–0.717
Coxsackievirus B3 (15)	0.017	0.01–0.195
Coxsackievirus B4 (10)	0.062	0.053–0.115
Coxsackievirus B5 (16)	0.007	0.004–0.40
Echovirus 3 (15)	0.050	0.007–0.463
Echovirus 4 (18)	0.009	0.002–0.206
Echovirus 5 (8)	0.04	0.01–0.10
Echovirus 6 (19)	0.005	0.002–0.014
Echovirus 7 (11)	0.014	0.005–1.26
Echovirus 9 (9)	0.024	0.004–0.057
Echovirus 11 (20)	0.002	0.0006–0.007
Echovirus 24 (12)	0.01	0.0009–0.80
Echovirus 30 (21)	0.009	0.002–0.042