Table 1.

Concurrent criterion validity for each algorithmic classification of early cognitive impairment (ECI) with consensus diagnosis and global cognitive scores.

Algorithmic classification of early cognitive impairment	AUC	95% Confidence interval	Sensitivity	Specificity	Kappa	N*	TP	FP	FN	TN
Consensus diagnosis of MCI/dementia
impairment in Card Rotation or CVLT immediate recall	0.631	0.588–0.674	0.52	0.74	0.03	9466	67	2443	61	6895
impairment in 1+ memory or 3+ non-memory tests	0.700	0.658–0.743	0.65	0.75	0.04	9524	85	2327	45	7067
Global cognitive scores
MMSE score (≤26)
impairment in Card Rotation or CVLT immediate recall	0.640	0.622–0.657	0.51	0.77	0.17	7551	416	1563	398	5174
impairment in 1+ memory or 3+ non-memory tests	0.670	0.652–0.688	0.56	0.78	0.21	7551	457	1492	357	5245
CDR-SB score (≥0.5)
impairment in Card Rotation or CVLT immediate recall	0.586	0.565–0.608	0.36	0.81	0.18	2073	264	254	466	1089
impairment in 1+ memory or 3+ non-memory tests	0.610	0.588–0.631	0.40	0.82	0.23	2073	295	248	435	1095
BIMC score (≥4)
impairment in Card Rotation or CVLT immediate recall	0.623	0.606–0.639	0.48	0.76	0.16	8892	506	1860	543	5983
impairment in 1+ memory or 3+ non-memory tests	0.659	0.644–0.675	0.54	0.78	0.21	8892	565	1727	484	6116

Note. MCI=mild cognitive impairment. CVLT=California Verbal Learning Test. MMSE=Mini-Mental State Examination. CDR-SB=Clinical Dementia Rating - Sum of Boxes. BIMC=Blessed Information Memory Concentration test. AUC=area under the curve. TP=true positive. FP=false positive. FN=false negative. TN=true negative.

Poor performance in global cognitive score was determined based on MMSE≤26, BIMC≥4, and CDR-SB≥0.5.

^*Number of visits among all eligible participants with available cognitive data.