Table 2: SCC-related histologic observations.

Full list of observations is in Table S1.

	Group
	1A	1B	2A	2B	3A	3B
	8 mice	9 mice	9 mice	9 mice	8 mice	8 mice
Invasive SCC ‡	10	11	13 (12)	13 (9)	5 (5)	1 (1)
Premalignant SCC #	40	30	32 (23)	22 (20)	23 (19)	28 (22)
Papilloma §	0	1	1 (1)	0 (0)	0 (0)	0 (0)

^‡fully and microinvasive SCC tumors;

^#all preneoplastic/pre-malignant observations;

^§Exophytic papilloma/ fibropapilloma; Numbers in brackets are observations for female mice only for the groups that included 1-2 male mice.