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. Author manuscript; available in PMC: 2023 Oct 23.
Published in final edited form as: Cell Rep. 2023 May 24;42(6):112540. doi: 10.1016/j.celrep.2023.112540

Figure 2. MetPch is only produced by S. aureus strains harboring spm.

Figure 2.

(A) Dendrogram of Spm (SAUSA300_1977) orthologs in staphylococcal species. Dendrogram was constructed based on KEGG database entries. *Coagulase-negative staphylococcal species.

(B) Genetic environment of spm (SAUSA300_1977) in six sequenced S. aureus strains. The gene spm is encoded in a putative operon with fhuD1.

(C) MetPch was detected from cultures of S. aureus strains encoding the spm gene but not by spm-negative strains (UAMS-1, MN8) when incubated with PAO1 ΔpqsA supernatant. n = 4 biological replicates. Values are mean ± SDs.