Figure 3:

Renal Function. Blood urea nitrogen (BUN) at 24-hours in mice exposed to hypoxia, normoxia, moderate hyperoxia, and severe hyperoxia during renal IR surgery (A) and sham IR surgery (B). Effect of hyperoxia treatment determined by Jonckheere-Terpstra test for trend across normoxia, moderate hyperoxia, and severe hyperoxia groups. * indicates p <0.05 for comparison between animals administered hypoxia vs. normoxia and # indicates p<0.05 for comparison of tempol vs. vehicle within each oxygen treatment, determined by Mann-Whitney U-Test.