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[Preprint]. 2023 Oct 9:2023.10.09.561507. [Version 1] doi: 10.1101/2023.10.09.561507

Figure 13.

Figure 13.

Docking of the SH2 domain of uSTAT1 onto the active state of the (JAK1/IFNλR1)2 complex for modeling of the active TYK2-IFNαR1/JAK1-IFNβR1 complex. (A) Two orthogonal views of the active complex colored by domains. (B) Two orthogonal views of the complex with docked SH2 domains in rainbow colors. (C) Two orthogonal views of the product parallel pSTAT1 just being assembled by the complex. See Video 7 for animation.