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[Preprint]. 2023 Oct 9:2023.10.09.561507. [Version 1] doi: 10.1101/2023.10.09.561507

Figure 6.

Figure 6.

Modeled full-length TYK2 in the autoinhibited state in complex with IFNαR1. (A) Two orthogonal views. Locations of pY residues upon activation are large balls-and-sticks models. (B) A closeup view of the JH2-JH1 interface. (C) Two back and front closeup views of the FERM-SH2/JH1 interface. See Video 2 for animation.