TABLE 1.

Range of MECs and MICs of drugs for different Aspergillus spp.

Species (no. of isolates)	Antifungal agent	MEC or MIC (mg/liter)a
		Range	50%	90%
A. fumigatus (35)	LY in AM3	0.0018–0.015	0.0018	0.0075
	LY in CAS	0.0018–0.015	0.0075	0.0075
	ITZ	0.25–>16	0.5	2
	AMB	0.5–2	2	2
A. terreus (8)	LY in AM3	0.0018–0.003	0.0018	0.003
	LY in CAS	0.0075–0.003	0.003	0.0075
	ITZ	0.125–0.25	0.25	0.25
	AMB	4–8	4	8
A. flavus (8)	LY in AM3	0.015–>0.5	0.015	1
	LY in CAS	0.0075–>0.5	0.03	1
	ITZ	0.5–8	0.5	4
	AMB	2–16	4	4
A. niger (8)	LY in AM3	0.0018–0.003	0.003	0.003
	LY in CAS	0.0075–0.015	0.0075	0.0075
	ITZ	0.5–>16	1	8
	AMB	0.25–1	1	1
A. nidulans (1)	LY in AM3	0.003	NCb	0.003
	LY in CAS	0.0075	NC	0.0075
	ITZ	0.125	NC	0.125
	AMB	2	NC	2
All isolates (60)	LY in AM3	0.0018–>0.5	0.003	0.015
	LY in CAS	0.0018–>0.5	0.0075	0.015
	ITZ	0.125–>16	0.5	8
	AMB	0.25–16	2	4

^aMEC₅₀ and MEC₉₀, for LY only; MIC₅₀ and MIC₉₀, for ITZ and AMB. 

^bNC, not calculable.